Pathophysiology Module 9
endocrine, paracrine, autocrine -
endocrine: hormones are released into circulation to act on a target organ๎โ๏ธ๎
paracrine: hormones act locally on cells close to where they are released
autocrine: hormones produce a biologic action on the cell that released them
transport carriers on which hormones? -
peptide and protein hormones: unattached โ๏ธ๎
steroid hormones: carrier protein
what are the different structural types of hormones? -
amines and amino acids โ๏ธ๎
peptides and proteins
steroids, made from cholesterol
function of hypothalamus -
link between NS and endocrine โ๏ธ๎
regulates homeostasis, body temp, hunger, behavior. emotion, pain
produces releasing hormones which stimulate pituitary to release stimulating hormones
What is the role of the pituitary gland? -
"master gland," โ๏ธ๎
stimulates target organs to secrete their hormones
anterior pituitary hormones -
GH, ACTH, TSH, FSH, LH, prolactinโ๏ธ๎
posterior pituitary hormones -
ADH and oxytocinโ๏ธ๎
ways hormones can be oversecreted -
1. target gland over-secretes due to pathologyโ๏ธ๎
2. pituitary or hypothalamus over-stimulates target gland
3. hormones produced from different site (tumor)
4. hyperactive genetic mutation of target hormone receptors
ways decreased hormone secretion happens -
1. congenital or acquired disorder of target gland โ๏ธ๎
