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Pharm Study Guide Review Solutions
NERVOUS SYSTEM
Benzodiazepines
• Alprazolam
• Diazepam
• Lorazepam
• Chlordiazepoxide
• Sedation
• Dependency/Withdrawal - Short term
• Antidote is Flumazenil
Atypical Anxiolytics
• Buspirone
• No Sedation - No Dependency - Long term
• Full effects take weeks
• Take with meals
SSRIs
• Paroxetine
• Sertraline
• Fluoxetine
•Insomnia
•Watch for Serotonin Syndrome (Agitation, Hallucinations, Fever,
Diaphoresis, Tremors)
•Do Not Take With St. John’s Wort
•Full Effects take months
Atypical Antidepressants
• Bupropion
• Trazodone (Major Side Effect - Sedation)
• Depression & Smoke Cessation
•Insomnia, headache, GI Distress, Weight Loss, Agitation, Seizures
TCAs
• Amitriptyline
• Imipramine
• Sedation, orthostatic hypotension Anticholinergic Effects (Urinary
Retention, Constipation, Dry Mouth, Blurry Vision, Photophobia)
MAOIs
• Phenelzine
• Tranylcypromine
•HTN Crisis
•Do not eat foods with tyramine
