pharmacokinetic phase
pharmacokinetic -
process of drug movement to achieve drug action
what are the four phases of pharmacokinetic -
absorption distribution metabolism and excretion
absorption -
the movement of drug particles from the GI tract to body fluids by passive absorption, active
absorption and pinocytosis
passive absorption -
occurs mostly by diffusion, doesn't require energy to move across membrane
active absorption -
requires a carrier such as an enzyme or portion to move the drug against a concentration
gradient
pinocytosis -
cells carry a drug across their membrane by engulfing the drug particles
distribution -
the drug becomes available to body fluids and body tissues
what three qualities of distribution will result in a pharmacologic effect -
protein binding, blood flow and body tissue affinity
metabolism -
