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A wide range of pharmacological topics and medical conditions, including information on drug interactions, adverse effects, treatment guidelines, and diagnostic tests. It addresses questions related to antihypertensive medications, antibiotic therapies, cardiovascular diseases, endocrine disorders, ophthalmological conditions, and more. The level of detail and breadth of topics suggest this document could be useful for medical students, healthcare professionals, or individuals with a strong interest in pharmacology and clinical medicine. The information provided could serve as a reference for study notes, lecture materials, or exam preparation, helping to solidify understanding of key concepts and clinical applications.
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INR values below ____ increase stroke risk sixfold. - ANSWER What allergy contradicts the use of thiazide diuretics? - ANSWERSulfa Why should ACE-Is be avoided with renal stenosis? - ANSWERLeads to ARF Adverse effects of aldosterone antagonists (Aldactone) - ANSWERGalactorrhea and hyperkalemia What are beta blocker indications? - ANSWERHTN, post-MI< angina, arrhythmias, migraine prophylaxis, hyperthyroidism 1st line BP med for DM? - ANSWERACE or ARB Grapefruit juice should be avoided in what 1st line antihypertensive medication? - ANSWERCCB Alternative antibiotic treatment for patients with gram positive baterial infections that are allergic to PCN: - ANSWERmacrolides Initial treatment of COPD - ANSWERIpratropium bromide (anticholinergic) 1st line treatment for gonorrheal infections - ANSWERRocephin IM Treatment of anthrax - ANSWERCipro 500mg BID 7-10 days Treatment of traveler's diarrhea - ANSWERCipro 500mg BID 3 days What can increase the risk of tendon rupture when on a quinolone? - ANSWERage and steroids How long does ASA suppress platelet function? - ANSWERup to 7 days What is the FDA category and dose of finasteride? - ANSWER5mg PO QD and category X What drug category should not be given with warfarin? - ANSWERsulfa drugs When should routine screening for breast cancer start? - ANSWER
If a patient had only one dose of the hep B vaccine what is recommended? - ANSWERDo not restart series; Start with 2nd dose What is done if a patient has a tetanus-prone wound and an unknown vaccination status? - ANSWERAdminister immediate dose of Td and the teatnus immunoglobulin injection If a person is vaccinated with pneumovax prior to 65 what is recommended? - ANSWERGive a booster dose of pneumovax 5 years after initial dose When should Zostavax be given? - ANSWERage 60 How far apart should the varicella vaccines be given? - ANSWER4 weeks Treatment for otitis externa - ANSWERCortisporin otic drops Common bacterial pathogen of otitis externa - ANSWERPseudomonas What is cholesteatoma a complication of? - ANSWERperiorbital sinusitis What indicates an abnormal Rinne test? - ANSWERBC>AC What kind of hearing loss is found with an abnormal Rinne if BC>AC? - ANSWERconductive What kind of hearing loss is associated with lateralization to affected ear when Weber test is performed - ANSWERConductive What kind of hearing loss is associated with lateralization to unaffected ear when Weber test is performed - ANSWERsensorurial What does 20/40 vision mean? - ANSWERA person can see 20 ft whereas normal vision can see 40 Common treatment of cerumenosis - ANSWERCarbamide peroxide What route should HIV esophageal candida infections - ANSWEROral systemic Where is a scabies rash located? - ANSWERInterdigital webs and/or penis Antibiotic treatment for human, dog, or cat bite - ANSWERAugmentin A herald patch or "Christmas tree" pattern is associated with what disease? - ANSWERPItyriasis rosea What class of meds are used to treat PHN? - ANSWERTCAs
Should you lower a markedly high triglyceride level or cholesterol first? - ANSWERTriglycerides Criteria for metabolic syndrome: - ANSWERAbdominal obesity, HTN, hyperlipidemia, high triglycerides, high fasting glucose What are characteristics of fatty liver disease? - ANSWERMild elevation of ALT & AST not associated with alocohol, meds, or viral hep in overweight patients What is used to calculate PEF? - ANSWERHeight, age, gender (HAG) When treating a COPD patient with antibiotics what organism (s) must the antibiotic cover? - ANSWERH. influenzae (gram negative) No. 1 bacterium in CAP - ANSWERStrep pneumo No. 1 atypical pneumonia - ANSWERMycoplasma pneumoniae At what mm is a PPD considered positive with no risk factors? - ANSWER15mm At what mm is a PPD considered positive in HIV? - ANSWER5mm What class of medications is 1st line treatment for asthma prevention? - ANSWERInhaled corticosteroids 1st line treatment for severe asthmatic exacerbation - ANSWERadrenaline injection Why should patients have annual eye exams when on long-term steroids - ANSWERincreases the risk of cataracts and glaucoma What is the definition of subclinical hypothyroidism - ANSWERElevated TSH and normal serum free T Which antidiabetic drugs are contraindicated in heart failure or severe heart disease and why? - ANSWERGlitizones because they can cause water retention How is the psoas maneuver performed? - ANSWER Which hepatitis is associated with the highest risk of cirrhosis and liver cancer? - ANSWERHep C When is nitrofurantoin contraindicated? - ANSWERrenal insufficiency What indicates pyelonephritis on a u/a microscopic? - ANSWERWBC casts with proteinuria
What is the best indicator of renal function? - ANSWEReGFR Treatment for temporal arteritis: - ANSWERhigh-dosed prednisone for several weeks Screening test for temporal arteritis - ANSWERSed rate What HA is treated with high dosed oxygen - ANSWERCluster What HA is treated with high-dosed anticonvulsants? - ANSWERTrigeminal neuralgia What HA is accompanied by tearing and nasal congestion? - ANSWERCluster What is the diagnostic test of thalassemia and sickle cell anemia? - ANSWERHemoglobin electrophoresis What two tests indicate that a patient has pernicious anemia if they are elevated? - ANSWERparietal antibody test and/or intrinsic factor antibody test What lab value indicates RBC size? - ANSWERMCV What anemia manifests with neurologic symptoms? - ANSWERB Where are Heberden's nodes located? - ANSWERDistal interphalangeal joint (DIP) How is uveitis treated? - ANSWERHigh-dose steroids; refer to opthalmology How does a Baker's cyst present? - ANSWERLocated behind the knee (popliteal fossa) as a ball-like mass 1st line treatment for ankolysing spondilytis? - ANSWERNSAIDS What medical conditions do antipsychotics increase the risk of (5)? - ANSWERobesity, DMII, hyperlipidemia, metabolic syndrome, and hypothyroidism What foods are high in tyramine? - ANSWERfermented-beer, wine, aged cheese, fava beans What is the FDA black box warning for SSRIs? - ANSWERMay increase the risk of suicidal thoughts/behaviors in children, adolescents, and young adults What causes Korsakoff's syndrome? - ANSWERChronic thiamine deficiency Can a patient smoke while on Zyban? - ANSWERyes What SSRI should be weaned? - ANSWERParoxetine
Most common cause of blindness in the US - ANSWERmacular degeneration 1st line treatment for essential tremors - ANSWERbeta blockers What occurs at Kiesselbach's plexus? - ANSWERAnterior nosebleed What ligament is damaged in a positive anterior drawer test? - ANSWERanterior cruciate ligament What is tonus palatinus? - ANSWERA chronic bony growth located midline in hard palate Which drugs increase hyperbilirubinemia in the 3rd trimester? - ANSWERNitrofurantoin and sulfa drugs Most common gynecological cancer - ANSWERUterine Examples of gluten - ANSWERwheat, rye, barley, oats Examples of plant sterols and steols - ANSWERwheat germ, sesame oil, corn oil, peanuts Examples of monounsaturated fats - ANSWERolive oil, canola oil, almonds, walnuts, sunflowers Examples of foods with magnesium - ANSWERalmonds, peanuts, cashews, some beans, whole wheat Example of foods with iron - ANSWERliver, beef, black beans Signs and symptoms of RMSF - ANSWERpetechiae rash on hands/feet, headache, myalgia, conjunctival injection, nausea/vomiting, arthralgia Diagnostic screening for herpes keratitis - ANSWERFluorescein lamp Signs of acute angle-closure glaucoma - ANSWERSudden onset of severe eye pain with headache, n/v, halos, decreased vision, cupping of the optic nerve A maculopapular rash that is oval-shaped with herald patch (disease) - ANSWERpityriosis rosea Where is the best location to auscultate the S3 heart sound? - ANSWERpulmonic area Drugs that have a narrow therapeutic index - ANSWERWarfarin, digoxin, lithium, levothyroxine, theophylline, tegretol, dilatin
What is the black box wearing of aldosterone antagonists? - ANSWERincreases benign and malignant tumors When are beta blockers contraindicated? - ANSWERasthma, COPD, chronic bronchitis, emphysema, bradycardia, and AV-block What bacteria do 1st generation cephalosporins act on? - ANSWERgram positive What bacteria do 2nd generation cephalosporins act on? - ANSWERgram negative and gram positive What bacteria do 3rd generation cephalosporins act on? - ANSWERBoth gram positive and negative, however, poor gram positive coverage What is 1st line treatment of MRSA? - ANSWERBactrim DS or clindamycin Which abx should not be used with mono? - ANSWERampicillin or amoxicillin What bacteria do sulfonamides act on? - ANSWERgram negative When is LAIV contraindicated? - ANSWERPregnancy, asthma, COPD, renal failure, DM, immunosuppression, What is larger in the eyes-veins or arteries? - ANSWERveins What diagnostic tool is used to assess for fluid in the middle ear? - ANSWERTympanogram Appearance of nasal turbinates in allergic rhinitis - ANSWERBluish, pale, boggy Description of Koplik spots - ANSWERsmall sized papules with blue-white center inside the cheek What is a pinguecula? - ANSWERA yellow-triangular thickening of the bulbar conjunctiva What disease is a sandpaper-textured pink rash found in: - ANSWERScarlet fever Description of basal cell carcinoma - ANSWERpearly or waxy skin lesion with atrophic or ulcerated center that does not heal What drug classes are higher risk for Steven Johnson's syndrome - ANSWERdilantin, PCN, sulfas, barbituates Is a thyroid cancer nodule hot or cold? - ANSWERCold