PHRM 4200- Solubility Test With

Complete Solution

Where must a drug be in order to work? - Answer in solution

What is the importance of the blood concentration/time graphs? - Answer important for

therapeutic windows

solvation - Answer the transfer of molecules or ions into the solvent (aka dissolution)

hydration - Answer the transfer of molecules or ions into water (solvation when water is

the solvent)

solubility - Answer the amount of solute needed to form a saturated solution in a given

quantity of solvent and experimental conditions

saturated solution - Answer when no more solid will dissolve and a dynamic equilibrium

exists between the solution and the undissolved solid

At what saturation is a solution in dynamic equilibrium? - Answer saturated solution

precipitation - Answer the opposite of solvation; the solvent cannot accommodate more

solute, so the solute precipitates back into solid form (aka crystallization)

What are the 2 opposing processes? - Answer solvation/dissolution and

precipitation/crystallization

cohesion - Answer attraction between molecules of the same substance

adhesion - Answer attraction between molecules of different substances

intermolecular forces - Answer the ability of the solvent to break up the cohesive forces

between solute particles and create adhesive forces

and the ability of the solute to break apart

What are the 6 types of intermolecular forces? - Answer - ion-dipole

- H bond

- dipole-dipole

- ion-induced dipole

- dipole-induced dipole

- London dispersion forces