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A comprehensive overview of the structure and functions of the plasma membrane, which is the outermost layer of a cell and serves as a barrier between the cell and its external environment. It covers the different types of integral proteins, their roles, and how they interact with the lipid bilayer. The document also discusses the importance of membrane fluidity, the role of cholesterol, and the consequences of hereditary defects in membrane proteins. Additionally, it outlines the four main functions of the plasma membrane: physical barrier, selective permeability, electrochemical gradients, and communication. This information is valuable for students studying cell biology, biochemistry, and related fields, as it provides a deep understanding of the fundamental structure and functions of this crucial cellular component.
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6 categories of integral proteins - answer โ โ pumps channels receptors linkers enzymes structural proteins a defect in spectrin or ankyrin causes - answer โ โ an abnormal arrangement of the internal cytoskeleton all of the carb chains on the E face (facing the extracellular fluid) collectively are called - answer โ โ the glycocalyx amphipathic means - answer โ โ 2 parts- hydrophilic and hydrophobic
carb chain attached to the membrane phospholipids is called - answer โ โ a glycolipid carb chain attached to the membrane proteins is called
communication location of integral proteins - answer โ โ firmly embedded in the lipid layers major constituents of the membrane (50% weight) - answer โ โ proteins peripheral proteins location - answer โ โ on the E or P face held in place by cytoskeleton filaments plasma membrane is also called the _____ or _____ - answer โ โ cell membrane, plasmalemma spectrin functions - answer โ โ works with ankyrin to stabilize the cell membrane of red blood cells straight chains are - answer โ โ saturated the chains face - answer โ โ the inside, towards each other (away from water)
the fatty acid chains in a phospholipid are called (abrv)
what is the excessive breakdown of rbc - answer โ โ hemolysis what is the function of a channel (integral protein)? - answer โ โ allowing passive diffuse of small molecules, ions, and water gap junction is formed by aligned channels what is the function of a enzymes (integral protein)? - answer โ โ ex: ATPases for ion pumping, ATP synthase in the inner membrane of mitochondria, disaccharides, and dipeptidases what is the function of a linker (integral protein)? - answer โ โ to anchor the intracellular cytoskeleton to the extracellular matrix ex: integrin family that links cytoplasmic actin filaments to an extracellular matrix protein (fibronectin) what is the function of a pump (integral protein)? - answer โ โ to transport certain ions, such as NA+, amino acids, and sugars
what is the function of a receptors (integral protein)? - answer โ โ allowing the ligands to bind to, such as hormones, antibodies, coated vesicle endocytosis what is the function of a structural proteins (integral protein)? - answer โ โ forming junction with neighboring cells what is the function of cholesterol? - answer โ โ acts as a fluidity buffer with changes in temperature fluidity-restriction of the movement of phospholipids what may an enlarged spleen case? - answer โ โ pain or fullness in the left upper abdomen that may spread to the left shoulder feeling of fullness without eating for after eating only a small amount from the enlarged spleen pressing on your stomach anemia fatigue frequent infections easy bleeding in some cases: no symptoms
