PORTAGE PATHOPHYSIOLOGY MODULE 3 EXAM, Exams of Advanced Education

PORTAGE PATHOPHYSIOLOGY MODULE 3 EXAM

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2025/2026

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PORTAGE PATHOPHYSIOLOGY
MODULE 3 EXAM
Explain the challenges of diagnosing autoimmune disorders. - CORRECT ANSWER
โœ”โœ”โœ” over 80 disorders, overlapping presentations, nonspecific manifestations that
are seen in other non-autoimmune diseases, blood testing isn't perfect as some are
generic
which cell is first responder to phagocytose foreign invader - CORRECT ANSWER
โœ”โœ”โœ” monocyte
primary cells involved in adaptive immune response? - CORRECT ANSWER โœ”โœ”โœ”
lymphocytes
T lymphocytes produce what type of immunity? - CORRECT ANSWER โœ”โœ”โœ” cell-
mediated
which immunoglobin provides local immunity on mucosal surfaces? - CORRECT
ANSWER โœ”โœ”โœ” IgA
which cell produces antibodies? - CORRECT ANSWER โœ”โœ”โœ” b lymphocyte
which feature not of innate immunity? - CORRECT ANSWER โœ”โœ”โœ” microbe
recognition is specific
12 year old female presents with itchy eyes, nasal congestion and drainage,
sneezing when pollen count is high.
1) explain immunologic mechanisms responsible for symptoms
2)what types of treatments used to relieve her symptoms? - CORRECT ANSWER
โœ”โœ”โœ” 1) mast cells, basophils, eosinophils play role in type I reactions since they
contain chemical mediators, histamine and heparin. primary response is
vasodilation, vascular leakage and smooth muscle contractions, secondary response
is more intense filtration of tissues with eosinophils and other acute and
inflammatory cells
2) antihistamines, intranasal corticosteroids
A narrow, surgical-type wound is likely to heal by secondary intention. - CORRECT
ANSWER โœ”โœ”โœ” false
which of following types of immunity are true about vaccines? select all that apply -
CORRECT ANSWER โœ”โœ”โœ” adaptive, humoral, active immunity
lymphocytes are categorized as either granulocytes or agranulocytes - CORRECT
ANSWER โœ”โœ”โœ” false
active immunity provides long lasting protection - CORRECT ANSWER โœ”โœ”โœ” true
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PORTAGE PATHOPHYSIOLOGY

MODULE 3 EXAM

Explain the challenges of diagnosing autoimmune disorders. - CORRECT ANSWER โœ”โœ”โœ” over 80 disorders, overlapping presentations, nonspecific manifestations that are seen in other non-autoimmune diseases, blood testing isn't perfect as some are generic which cell is first responder to phagocytose foreign invader - CORRECT ANSWER โœ”โœ”โœ” monocyte primary cells involved in adaptive immune response? - CORRECT ANSWER โœ”โœ”โœ” lymphocytes T lymphocytes produce what type of immunity? - CORRECT ANSWER โœ”โœ”โœ” cell- mediated which immunoglobin provides local immunity on mucosal surfaces? - CORRECT ANSWER โœ”โœ”โœ” IgA which cell produces antibodies? - CORRECT ANSWER โœ”โœ”โœ” b lymphocyte which feature not of innate immunity? - CORRECT ANSWER โœ”โœ”โœ” microbe recognition is specific 12 year old female presents with itchy eyes, nasal congestion and drainage, sneezing when pollen count is high.

  1. explain immunologic mechanisms responsible for symptoms 2)what types of treatments used to relieve her symptoms? - CORRECT ANSWER โœ”โœ”โœ” 1) mast cells, basophils, eosinophils play role in type I reactions since they contain chemical mediators, histamine and heparin. primary response is vasodilation, vascular leakage and smooth muscle contractions, secondary response is more intense filtration of tissues with eosinophils and other acute and inflammatory cells
  2. antihistamines, intranasal corticosteroids A narrow, surgical-type wound is likely to heal by secondary intention. - CORRECT ANSWER โœ”โœ”โœ” false which of following types of immunity are true about vaccines? select all that apply - CORRECT ANSWER โœ”โœ”โœ” adaptive, humoral, active immunity lymphocytes are categorized as either granulocytes or agranulocytes - CORRECT ANSWER โœ”โœ”โœ” false active immunity provides long lasting protection - CORRECT ANSWER โœ”โœ”โœ” true

passive immunity provides long lasting protection - CORRECT ANSWER โœ”โœ”โœ” false type I hypersensitivity reactions are _____ mediated reactions - CORRECT ANSWER โœ”โœ”โœ” IgE which cell doesnt play important role in type I hypersensitivity reactions? - CORRECT ANSWER โœ”โœ”โœ” CD4 T cells which is not type of type II hypersensitivity reaction? - CORRECT ANSWER โœ”โœ”โœ” atopy features of SLE include all of following except - CORRECT ANSWER โœ”โœ”โœ” exophthalmos what are autoantibodies? - CORRECT ANSWER โœ”โœ”โœ” when immune system loses ability to recognize self and produces autoantibodies that act against host tissues

  1. a 32-year woman presents to clinic for initial obstetrics visit about 10 weeks into pregnancy. she is in monogamous relationship. should HIV test be part of initial bloodwork why?
  2. infant is born, its initial antibody test is positive for HIV. does this mean infant is infected? what should be the more appropriate test? - CORRECT ANSWER โœ”โœ”โœ” 1) yes, transmission from mother to infant is common way children become infected, early detection and treatment leads to better outcomes
  3. no, polymerase chain reaction or PCR test detects HIV DNA, tests for presence of virus rather than antibody. infants would have mother's antibodies whether or not they have been infected. cells primarily responsible for tissue building during proliferative phase of wound healing are known as? - CORRECT ANSWER โœ”โœ”โœ” fibroblasts which of following not classified as labile or stable cells? - CORRECT ANSWER โœ”โœ”โœ” skeletal muscle cell As the CD4 T-cell count decreases, the body becomes susceptible to __________ infection. - CORRECT ANSWER โœ”โœ”โœ” opportunistic infections The term to describe the time when an infected person's blood converts from being negative for HIV antibodies to being positive is called what? - CORRECT ANSWER โœ”โœ”โœ” seroconversion person with HIV is not infectious when asymptomatic - CORRECT ANSWER โœ”โœ”โœ” false The T cells that display the host's MHC antigens and T-cell receptors for a nonself- antigen are allowed to mature, a process termed positive selection. - CORRECT ANSWER โœ”โœ”โœ” true process of leukocyte accumulation in cellular phase of acute inflammation is called?
  • CORRECT ANSWER โœ”โœ”โœ” margination