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Genetics 466: Problem Set #4 - Yeast Genetics and Gene Regulation, Assignments of Genetics

University of Wisconsin (UW) - MadisonGenetics

A problem set from a university genetics course focusing on yeast genetics and gene regulation. Students are expected to be familiar with various terms related to transcription factors, chromatin, histone modifications, and gene regulation. The problem set includes three questions, one of which asks about mutations in an α strain of yeast that prevents mating, another question asks about the genes regulated by α1, α2 in an α cell, and the third question is not provided in the document.

Typology: Assignments

Pre 2010

Uploaded on 09/02/2009

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Genetics 466
Fall 2008
Sean Carroll
1
PROBLEM SET #4 (lectures 22-23)
1. You should be knowledgeable about the following terms:
transcription factor
pheromone
co-activator
chromatin
co-repressor
upstream activating
sequence
enhancer
activation domain
recruitment
Gal pathway
Nucleosome
Chromatin remodeling
histone acetylation
histone deacetylation
glucose repression
Gal4, Gal80, Gal3, Mig1
mating-type
MAT locus
HO
α1, a2, a1
α−, a- factors/receptors
sporulation
cassette model
SWI genes
Cell-type specific genes
Cooperativity
Combinatorial regulation
enhanceosome
2. An α strain of yeast exists that will switch but cannot mate. What mutations
might it carry t hat would explain this?
3. What genes are regulated by an α1, α2 in an α cell?

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Genetics 466 Fall 2008 Sean Carroll 1 PROBLEM SET #4 (lectures 22-23)

  1. You should be knowledgeable about the following terms: transcription factor pheromone co-activator chromatin co-repressor upstream activating sequence enhancer activation domain recruitment Gal pathway Nucleosome Chromatin remodeling histone acetylation histone deacetylation glucose repression Gal4, Gal80, Gal3, Mig mating-type MAT locus HO α1, a2, a α−, a- factors/receptors sporulation cassette model SWI genes Cell-type specific genes Cooperativity Combinatorial regulation enhanceosome
  2. An α strain of yeast exists that will switch but cannot mate. What mutations might it carry that would explain this?
  3. What genes are regulated by an α1, α2 in an α cell?