Psychotic Disorders., Study notes of Abnormal Psychology

Into an basics about Psychotic Disorders with DSM criterion.

Typology: Study notes

2021/2022

Uploaded on 04/25/2023

unknown user
unknown user 🇮🇳

2 documents

1 / 19

Toggle sidebar

This page cannot be seen from the preview

Don't miss anything!

bg1
Psychotic Disorders
Schizophrenia-
the startling disorder characterized by a broad spectrum of cognitive and emotional
dysfunctions including delusions and hallucinations, disorganized speech and behavior, and
inappropriate emotions.
Schizophrenia is a complex syndrome that inevitably has a devastating effect on the lives of the
person affected and on family members. This disorder can disrupt a person’s perception,
thought, speech, and movement: almost every aspect of daily functioning. Society often
devalues these individuals. People with these severe mental health problems are more likely to
be stigmatized and discriminated against than those without schizophrenia
Schizophrenia affects one’s ability to express oneself clearly,To have close social relationships,
to express positive emotions and to plan for their future.
The most common set of symptoms seen in individuals with schizophrenia with the past 100
years is a belief that others are out to get them and the hearing of voices that others do not
hear.
Individuals schizophrenia can display problems in terms of cognitive process, emotion processes
and motor processes. Cognitive problems can be seen as a disorganization of thinking and
behavior.
the end of the 19th century, the German psychiatrist Emil Kraepelin (1899) built on the writings
of Haslam, Pinel, and Morel (among others) to give us what stands today as the most enduring
description and categorization of schizophrenia.
Two of Kraepelin’s accomplishments are especially important. First, he combined several
symptoms of insanity that had usually been viewed as reflecting separate and distinct disorders:
catatonia (alternating immobility and excited agitation), hebephrenia (silly and immature
emotionality), and paranoia (delusions of grandeur or persecution). Kraepelin thought these
symptoms shared similar underlying features and included them under the Latin term dementia
praecox. Although the clinical manifestation might differ from person to person, Kraepelin
believed an early onset at the heart of each disorder develops into “mental weakness.”
Kraeplin suggested there were four subtypes of dementia praecox. The first was the simple type
which was characterized by a slow decline along with social withdrawal and apathy. The second
was paranoid characterized by persecution.The third was hebephrenic characterized by mania
like presentation. The fourth was catatonia lack of movement.
In a second important contribution, Kraepelin (1898) distinguished dementia praecox from
manic-depressive illness (now called bipolar disorder). For people with dementia praecox, an
early age of onset and a poor outcome were characteristic; in contrast, these patterns were not
essential to manic depression, Kraepelin also noted the numerous symptoms in people with
dementia praecox, including hallucinations, delusions, negativism, and stereotyped behavior.
A second major figure in the history of schizophrenia was Kraepelin’s contemporary, Eugen
Bleuler (1908), a Swiss psychiatrist who introduced the term schizophrenia. Schizophrenia,
which comes from the combination of the Greek words for “split” (skhizein) and “mind” (phren),
reflected Bleuler’s belief that underlying all the unusual behaviors shown by people with this
disorder was an associative splitting of the basic functions of personality. This concept
pf3
pf4
pf5
pf8
pf9
pfa
pfd
pfe
pff
pf12
pf13

Partial preview of the text

Download Psychotic Disorders. and more Study notes Abnormal Psychology in PDF only on Docsity!

Psychotic Disorders

Schizophrenia-

  • the startling disorder characterized by a broad spectrum of cognitive and emotional dysfunctions including delusions and hallucinations, disorganized speech and behavior, and inappropriate emotions.
  • Schizophrenia is a complex syndrome that inevitably has a devastating effect on the lives of the person affected and on family members. This disorder can disrupt a person’s perception, thought, speech, and movement: almost every aspect of daily functioning. Society often devalues these individuals. People with these severe mental health problems are more likely to be stigmatized and discriminated against than those without schizophrenia
  • Schizophrenia affects one’s ability to express oneself clearly,To have close social relationships, to express positive emotions and to plan for their future.
  • The most common set of symptoms seen in individuals with schizophrenia with the past 100 years is a belief that others are out to get them and the hearing of voices that others do not hear.
  • Individuals schizophrenia can display problems in terms of cognitive process, emotion processes and motor processes. Cognitive problems can be seen as a disorganization of thinking and behavior.
  • the end of the 19th century, the German psychiatrist Emil Kraepelin (1899) built on the writings of Haslam, Pinel, and Morel (among others) to give us what stands today as the most enduring description and categorization of schizophrenia.
  • Two of Kraepelin’s accomplishments are especially important. First, he combined several symptoms of insanity that had usually been viewed as reflecting separate and distinct disorders: catatonia (alternating immobility and excited agitation), hebephrenia (silly and immature emotionality), and paranoia (delusions of grandeur or persecution). Kraepelin thought these symptoms shared similar underlying features and included them under the Latin term dementia praecox. Although the clinical manifestation might differ from person to person, Kraepelin believed an early onset at the heart of each disorder develops into “mental weakness.”
  • Kraeplin suggested there were four subtypes of dementia praecox. The first was the simple type which was characterized by a slow decline along with social withdrawal and apathy. The second was paranoid characterized by persecution.The third was hebephrenic characterized by mania like presentation. The fourth was catatonia – lack of movement.
  • In a second important contribution, Kraepelin (1898) distinguished dementia praecox from manic-depressive illness (now called bipolar disorder). For people with dementia praecox, an early age of onset and a poor outcome were characteristic; in contrast, these patterns were not essential to manic depression, Kraepelin also noted the numerous symptoms in people with dementia praecox, including hallucinations, delusions, negativism, and stereotyped behavior.
  • A second major figure in the history of schizophrenia was Kraepelin’s contemporary, Eugen Bleuler (1908), a Swiss psychiatrist who introduced the term schizophrenia. Schizophrenia, which comes from the combination of the Greek words for “split” (skhizein) and “mind” (phren), reflected Bleuler’s belief that underlying all the unusual behaviors shown by people with this disorder was an associative splitting of the basic functions of personality. This concept

emphasized the “breaking of associative threads,” or the destruction of the forces that connect one function to the next.

  • Bleuler was critical of the term dementia praecox and suggested that here were was not a single schizophrenia but a number of different disorders with diff etiologies and prognoses. Characterisitcs described by him-
  • a) Affect- blunted or diminished emotional response
  • b)associations-loosening or inability to think in a logical manner
  • c)ambivalence-inability to make decisions
  • d)autism-social aloofness and an inablilty to remain in contact with the external world. STAGES OF SCHIZOPHRENIA
  • The course of Schizophrenia generally begins in adolescence or young adulthood
    1. Premorbid Phase During this phase , only subtle or nospecific problems with cognition, motor, or social functioning can be detected. They are accompanied by poor academic achievement and social functioning.
  • 2 ) Prodormal Phase: Normal individuals show some bizarre ideas as well as a thinking process. They are normally studying, doing business & socio-cultural activities, gradually they don’t like to participate in social activity. Their level of hygiene is disturbed, vigour is weakened & they do not complete important tasks in a stipulated period. Expressions of emotions become vague. All these symptoms are seen for up to one or two years.
  • 3 ) Active Phase: In this phase, the individual experiences hallucinations as well as delusions. They are unable to maintain contact with reality. The behaviour is disorganized. Thinking & emotions seem to be contradictory.
  • 4 ) Residual Phase: Symptoms of schizophrenia disappear for a long time but suddenly the patient may suffer a relapse & start showing the symptoms of schizophrenia. POSITIVE SYMPTOMS DELUSIONS
  • Positive symptoms generally refer to symptoms around distorted reality. Negative symptoms involve deficits in normal behavior in such areas as speech, blunted affect (or lack of emotional reactivity), and motivation. Disorganized symptoms include rambling speech, erratic behavior, and inappropriate affect (for example, smiling when you are upset).
  • A belief that would be seen by most members of a society as a misrepresentation of reality is called a disorder of thought content, or a delusion. These are fixed beliefs that are not amenable to change in light of conflicting evidence. In simple terms, these are false beliefs. Their content may include a variety of themes:
  • i. Persecutory: A most common belief that one is going be harmed or harassed & so forth by an individual or organization or another group.
  • ii. Referential: A belief that certain gestures or comments or environmental cues & so forth are directed at oneself.
  • iii. Grandiose: when an individual believes falsely that he/she has exceptional abilities/ wealth/fame.
  • iv. Erotomanic: when an individual believes falsely that another person is in love with them.

the “speech” of others, you might expect more activity in Wernicke’s area, which involves language comprehension.

  • These observations support the metacognition theory that people who are hallucinating are not hearing the voices of others but are listening to their own thoughts or their own voices and cannot recognize the difference
  • One possible explanation for this problem is referred to as poor “emotional prosody comprehension.” Prosody is that aspect of our spoken language that communicates meaning and emotion through our pitch, amplitude, pauses, etc. Research suggests that emotional prosody is deficient in persons with auditory verbal hallucinations, contributing to the confusion both with others as well as when interpreting “inner voices” NEGATIVE SYMPTOMS
  • the negative symptoms usually indicate the absence or insufficiency of normal behavior. They include apathy, poverty of (i.e., limited) thought or speech, and emotional and social withdrawal, and approximately 25% of people with schizophrenia display these symptoms AVOLITION
  • Combining the prefix a, meaning “without,” and volition, which means “an act of willing, choosing, or deciding,” avolition is the inability to initiate and persist in activities. People with this symptom (also referred to as apathy) show little interest in performing even the most basic day-to-day functions, including those associated with personal hygiene. ALOGIA
  • Derived from the combination of a (“without”) and logos (“words”), alogia refers to the relative absence of speech. A person with alogia may experienced by some people with schizophrenia. Like some mood disorders, anhedonia signals an indifference to activities that would typically be considered pleasurable, including eating, social interactions, and sexual relations. ANHEDONIA
  • This word derives from the word hedonic, about pleasure. It is the presumed lack of pleasure experienced by some people with schizophrenia. The patient shows indifference to activities that are usually considered pleasurable involving, eating, social interactions & sexual relations. AFFECTIVE FLATTENING
  • they do not show emotions when you would normally expect them to. They may stare at you vacantly, speak in a flat and toneless manner, and seem unaffected by things going on around them. However, although they do not react openly to emotional situations, they may be responding on the inside.
  • Howard Berenbaum and Thomas Oltmanns concluded that the flat affect in schizophrenia may represent difficulty expressing emotion, not a lack of feeling. Researchers can now use computer analyses of facial expressions to more objectively assess the emotional expressiveness of people with disorders such as schizophrenia
  • The expression of affect—or the lack of this expression—may be an important symptom of the development of schizophrenia. DISORGANIZED SYMPTOMS A) DISORGANIZED SPEECH
  • A conversation with someone who has schizophrenia can be particularly frustrating. For one thing, people with schizophrenia often lack insight, an awareness that they have a problem. In addition, they experience what Bleuler called “associative splitting” and what researcher Paul Meehl called “cognitive slippage” (Bleuler, 1908; Meehl, 1962). These phrases help describe the speech problems of people with schizophrenia: Sometimes they jump from topic to topic, and at other times they talk illogically.
  • tangentiality—that is, going off on a tangent instead of answering a specific question. Individuals also abruply change topic of conversations to unrelated areas, a behavior that has variously been called loose association or derailment
  • Rarely, speech may be so severely disorganized that it is nearly incomprehensible. The language used is disorganized (incoherence/word salad). Inventing new words (neologisms). Mildly disorganized speech is common. The symptoms are at times severe enough to impair communication. B) INAPPROPRIATE AFFECT AND DISORGANIZED BEHAVIOR
  • Occasionally, people with schizophrenia display inappropriate affect, laughing or crying at improper times. Sometimes they exhibit bizarre behaviors such as hoarding objects or acting in unusual ways in public
  • People with schizophrenia engage in a number of other “active” behaviors that are usually viewed as unusual. For example, catatonia is one of the most curious symptoms in some individuals with schizophrenia; it involves motor dysfunctions that range from wild agitation to immobility.
  • DSM 5 now includes catatonia as a separate schizophrenia spectrum disorder. On the active side of the continuum, some people pace excitedly or move their fingers or arms in stereotyped ways. At the other end of the extreme, people hold unusual postures, as if they were fearful of something terrible happening if they move (catatonic immobility). This manifestation can also involve waxy flexibility, or the tendency to keep their bodies and limbs in the position they are put in by someone else.

Other Psychotic Disorders

  • the search for subtypes of schizophrenia began before Kraepelin described his concept of schizophrenia. Three divisions have historically been identified: paranoid (delusions of grandeur or persecution), disorganized (or hebephrenic; silly and immature emotionality), and catatonic (alternate immobility and excited agitation). Although these categories continued to be used in DSM-IV-TR, they were dropped from the diagnostic criteria for DSM- 5

Specify if: With good prognostic features: This specifier requires the presence of at least two of the following features: onset of prominent psychotic symptoms within 4 weeks of the first noticeable change in usual behavior or functioning; confusion or perplexity; good premorbid social and occupational functioning; and absence of blunted or flat affect. Without good prognostic features: This specifier is applied if two or more of the above features have not been present. Specify if: With catatonia

Schizoaffective Disorder

  • }Schizoaffective disorder is characterized by abnormal thought processes and dysregulated emotions.
  • }A person with this disorder has features of both schizophrenia and a mood disorder (either bipolar disorder or depression) but does not strictly meet the diagnostic criteria for either.
  • }Schizoaffective disorder symptoms may vary from person to person.
  • }People with the condition experience psychotic symptoms, such as hallucinations or delusions, as well as symptoms of a mood disorder — either bipolar type (episodes of mania and sometimes depression) or depressive type (episodes of depression).
  • }Although the development and course of schizoaffective disorder may vary, defining features include a major mood episode (depressed or manic mood) and at least a two-week period of psychotic symptoms when a major mood episode is not present.
  • }Signs and symptoms of schizoaffective disorder depend on the type — bipolar or depressive type — and may include, among others:
  • }Delusions — having false, fixed beliefs, despite evidence to the contrary
  • }Hallucinations, such as hearing voices or seeing things that aren't there
  • }Impaired communication and speech, such as being incoherent
  • }Bizarre or unusual behavior
  • }Symptoms of depression, such as feeling empty, sad or worthless
  • }Periods of manic mood, with an increase in energy and a decreased need for sleep over several days, and behaviors that are out of character
  • }Impaired occupational, academic and social functioning
  • }Problems with managing personal care, including cleanliness and physical appearance A. An uninterrupted period of illness during which there is a major mood episode (major depressive or manic) concurrent with Criterion A of schizophrenia . Note: The major depressive episode must include Criterion A1: Depressed mood. B. Delusions or hallucinations for 2 or more weeks in the absence of a major mood episode (depressive or manic) during the lifetime duration of the illness.

C. Symptoms that meet criteria for a major mood episode are present for the majority of the total durance of the active and residual portions of the illness. D. The disturbance is not attributable to the effects of a substance (e.g., a drug of abuse, a medication) or another medical condition. Specify whether: Bipolar type: This subtype applies if a manic episode is part of the presentation Major depressive episodes may also occur. Depressive type: This subtype applies only if only major depressive episodes are part of the presentation. Specify if: With catatonia

Brief Psychotic Disorder

  • }It is characterized by psychotic symptoms that come on suddenly but last only for a short time -
    • less than 1 month. After that, people usually recover completely.
  • }It involves a sudden onset which is defined as a change from a non-psychotic state to a clearly psychotic state within 2 weeks.
  • }The person may experience emotional turmoil or overwhelming confusion.
  • }Although the disturbance is brief, level of impairment may be severe. A. Presence of one (or more) of the following symptoms. At least one of these must be (1), (2), or (3):
  1. Delusions.
  2. Hallucinations.
  3. Disorganized speech (e.g., frequent derailment or incoherence).
  4. Grossly disorganized or catatonic behavior. Note: Do not include a symptom if it is a culturally sanctioned response B. Duration of an episode of the disturbance is at least 1 day but less than 1 month, with eventual full return to premorbid level of functioning. C. The disturbance is not better explained by major depressive or bipolar disorder with psychotic features, or another psychotic disorder such as schizophrenia or catatonia, and is not attributable to the physiological effects of a substance (e.g., a drug of abuse, a medication) or another medical condition. Specify if: With marked stressor(s) (brief reactive psychosis): If symptoms occur in response to events that, singly or together, would be markedly stressful to almost anyone in similar circumstances in the individual’s culture. Without marked stressor(s): If symptoms do not occur in response to events that, singly or together, would be markedly stressful to almost anyone in similar circumstances in the individual’s culture. With postpartum onset: If onset is during pregnancy or within 4 weeks postpartum.

symptoms become most disruptive. Delusional disorder seems to afflict more females than males A. The presence of one (or more) delusions with a duration of 1 month or longer. B. Criterion A for schizophrenia has never been met. Note: Hallucinations, if present, are not prominent and are related to the delusional theme (e.g., the sensation of being infested with insects associated with delusions of infestation). C. Apart from the impact of the delusion(s) or its ramifications, functioning is not markedly impaired, and behavior is not obviously bizarre or odd

. D. If manic or major depressive episodes have occurred, these have been brief relative to the duration of the delusional periods. E. The disturbance is not attributable to the physiological effects of a substance or another medical condition and is not better explained by another mental disorder, such as body dysmorphic disorder or obsessive-compulsive disorder. Specify whether:

Causes of Schizophrenia

GENETIC

  • Schizophrenia tends to run in families, but no single gene is thought to be responsible. It's more likely that different combinations of genes make people more vulnerable to the condition. However, having these genes does not necessarily mean you'll develop schizophrenia
  • According to major study of families by Franz Kallman the severity of the parent’s disorder influenced the likelihood of the child’s having schizophrenia: The more severe the parent’s schizophrenia, the more likely the children were to develop it.
  • All forms of schizophrenia (for example, the historic categories such as catatonic and paranoid) were seen within the families. In other words, it does not appear that you inherit a predisposition for what was previously diagnosed as paranoid schizophrenia. Instead, you may inherit a general predisposition for schizophrenia that manifests in the same form or differently from that of your parent
  • More recent research confirms this observation and suggests that families that have a member with schizophrenia are at risk not just for schizophrenia alone or for all psychological disorders; instead, there appears to be some familial risk for a spectrum of psychotic disorders related to schizophrenia.
  • In a classic analysis, Gottesman (1991) summarized the data from about 40 studies of schizophrenia, as shown in ● Figure 13.3. The most striking feature of this graph is its orderly demonstration that the risk of having schizophrenia varies according to how many genes an individual shares with someone who has the disorder. For example, you have the greatest

chance (approximately 48%) of having schizophrenia if it has affected your identical (monozygotic) twin, a person who shares 100% of your genetic information. Your risk drops to about 17% with a fraternal (dizygotic) twin, who shares about 50% of your genetic information. And having any relative with schizophrenia makes you more likely to have the disorder than someone without such a relative (about 1% if you have no relative with schizophrenia).

  • In one of the most fascinating of “nature’s experiments,” identical quadruplets, all of whom have schizophrenia, have been studied extensively. Nicknamed the “Genain” quadruplets (from the Greek, meaning “dreadful gene”), these women have been followed by David Rosenthal and his colleagues at the National Institute of Mental Health for a number of years (Rosenthal, 1963). The fictitious names of the girls reported in studies of their lives—Nora, Iris, Myra, and Hester—represent the letters NIMH for the National Institute of Mental Health. In a sense, the women represent the complex interaction between genetics and environment.
  • All four shared the same genetic predisposition, and all were brought up in the same particularly dysfunctional household; yet the time of onset for schizophrenia, the symptoms and diagnoses, the course of the disorder, and, ultimately, their outcomes, differed significantly from sister to sister.
  • The case of the Genain quadruplets also reveals an important consideration in studying genetic influences on behavior—unshared environments Even identical siblings can have different prenatal and family experiences and can therefore be exposed to varying degrees of biological and environmental stress
  • The largest adoption study was conducted in Finland The data from this study support the idea that schizophrenia represents a spectrum of related disorders, all of which overlap genetically
  • If an adopted child had a biological mother with schizophrenia, that child had about a 5% chance of having the disorder (compared to about only 1% in the general population). However, if the biological mother had schizophrenia or one of the related psychotic disorders (for example, delusional disorder or schizophreniform disorder), the risk that the adopted child would have one of these disorders rose to about 22%
  • Even when raised away from their biological parents, children of parents with schizophrenia have a much higher chance of having the disorder themselves. At the same time, there appears to be a protective factor if these children are brought up in healthy supportive homes. In other words, a gene–environment interaction was observed in this study, with a good home environment reducing the risk of schizophrenia
  • Researchers in a study begun in 1971 by Margit Fischer and later continued by Irving Gottesman and Aksel Bertelsen wanted to determine the relative likelihood that a child would have schizophrenia if her parent did and if the parent’s twin had schizophrenia but the parent did not.
  • If your parent is the twin with schizophrenia, you have about a 17% chance of having schizophrenia yourself. If your parent does not have schizophrenia but your parent’s fraternal twin does, your risk is only about 2%. The data clearly indicate that you can have genes that predispose you to schizophrenia, not show the disorder yourself, but still pass on the genes to your children. In other words, you can be a “carrier” for schizophrenia
  • Evidence that the disorder is partly inherited comes from studies of twins. Identical twins share the same genes. In identical twins, if a twin develops schizophrenia, the other twin has a 1 in 2 chance of developing it, too. This is true even if they're raised separately.
  • As early as 1927, these liquid-filled cavities showed enlargement in some brains examined in people with schizophrenia
  • Since then, more sophisticated techniques have been developed for observing the brain, and in the dozens of studies conducted on ventricle size, the great majority show abnormally large lateral and third ventricles in people with schizophrenia
  • Ventricle size may not be a problem, but the dilation (enlargement) of the ventricles indicates that adjacent parts of the brain either have not developed fully or have atrophied, thus allowing the ventricles to become larger.
  • enlarged ventricles are observed more often in men than in women, One study found that individuals with schizophrenia who were exposed to influenza prenatally may be more likely to have enlarged ventricles
  • Using a brain-imaging technique, magnetic resonance imaging (MRI), investigators compared brain structure among people with schizophrenia, their same-sex siblings who did not have schizophrenia, and healthy volunteers. Both the people with schizophrenia and their otherwise unaffected siblings had enlargement of the third ventricle compared with the volunteers. This suggests that the enlargement of ventricles may be related to susceptibility to schizophrenia.
  • The frontal lobes of the brain have also interested researchers looking for structural problems associated with schizophrenia, in the section on neurotransmitters, this area may be less active in people with schizophrenia than in people without the disorder, a phenomenon sometimes known as hypofrontality (hypo means “less active,” or “deficient”).
  • Research by Weinberger and other scientists at the National Institute of Mental Health further refined this observation, suggesting that deficient activity in a particular area of the frontal lobes, the dorsolateral prefrontal cortex (DLPFC), may be implicated in schizophrenia
  • With its involvement with executive function tasks such as planning and social tasks, the frontal lobes have been extensively studied.
  • Current research examining individuals with gizmo frena has emphasized five different levels of analysis from a neuroscience perspective. The first is anatomical changes such as the loss of brain volume in particular areas. The second is functional process such as the manner in which cortical areas and network process information as seen in the brain imaging. The third is neural oscillations that underlie the cortical networks. The 4th^ is changes in neurotransmitters such as dopamine gaba, glycine and glutamate. The 5th is development Of cortical process beginning in the utero. FAMILIES AND RELAPSE
  • e, the term schizophrenogenic mother was used for a time to describe a mother whose cold, dominant, and rejecting nature was thought to cause schizophrenia in her children (Fromm- Reichmann, 1948)
  • In addition, the term double bind communication was used to portray a communication style that produced conflicting messages, which, in turn, caused schizophrenia to develop
  • Recent work has focused more on how family interactions contribute not to the onset of schizophrenia but to relapse after initial symptoms are observed.
  • Research has focused on a particular emotional communication style known as expressed emotion (EE). This concept was formulated by George W. Brown and his colleagues in London.
  • Additional research results indicated that if the levels of criticism (disapproval), hostility (animosity), and emotional overinvolvement (intrusiveness) expressed by the families were high, patients tended to relapse
  • Other researchers have since found that ratings of high expressed emotion in a family are a good predictor of relapse among people with chronic schizophrenia. This style suggests that families with high expressed emotion view the symptoms of schizophrenia as controllable and that the hostility arises when family members think that patients just do not want to help themselves PRENATAL AND PERINATAL INFLUENCE S
  • There is evidence that the prenatal (before birth) and perinatal (around the time of birth) environment are correlated with the development of schizophrenia. Fetal exposure to viral infection, pregnancy complications, and delivery complications are among the environmental influences that seem to affect whether or not someone develops schizophrenia.
  • Several studies have shown that schizophrenia may be associated with prenatal exposure to influenza. For example, Sarnoff Mednick and colleagues followed a large number of people after a severe Type A2 influenza epidemic in Helsinki, Finland, and found that those whose mothers were exposed to influenza during the second trimester of pregnancy were more likely to have schizophrenia than others
  • The indications that viruslike diseases may cause damage to the fetal brain, which later may cause the symptoms of schizophrenia, are suggestive and may help explain why some people with schizophrenia behave the way they do
  • The evidence of pregnancy complications (for example, bleeding) and delivery complications (for example, asphyxia or lack of oxygen) and their relationship to later schizophrenia suggest, on the surface, that this type of environmental stress may trigger the expression of the disorder, It is possible, however, that the genes carried by the fetus that make it vulnerable to schizophrenia may themselves contribute to the birth complications (
  • The chronic and early use of marijuana (cannabis) is also being studied as a potential influence on the onset of schizophrenia

Treatment for Schizophrenia

  • in the 1500s primitive surgery was conducted to remove the “stone of madness,” which was thought to cause disturbed behavior. As barbaric as this practice may seem today, it is not different from the prefrontal lobotomies performed on people with schizophrenia as late as the 1950s BIOLOGICAL INTERVENTIONS
  • During the 1930s, several novel biological treatments were tried. One approach was to inject massive doses of insulin—the drug that given in smaller doses is used to treat diabetes—to induce comas in people suffering from schizophrenia. Insulin coma therapy was thought for a time to be helpful, but closer examination showed it carried great risk of serious illness and death.

involuntary movements of the tongue, face, mouth, or jaw and can include protrusions of the tongue, puffing of the cheeks, puckering of the mouth, and chewing movements.

  • Tardive dyskinesia seems to result from long-term use of high doses of antipsychotic medication and is often irreversible
  • An interesting treatment for the hallucinations experienced by many people with schizophrenia involves exposing the individual to magnetic fields. Called transcranial magnetic stimulation,
  • this technique uses wire coils to repeatedly generate magnetic fields—up to 50 times per second—that pass through the skull to the brain. This input seems to interrupt temporarily the normal communication to that part of the brain. Hoffman and colleagues (2000, 2003) used this technique to stimulate the area of the brain involved in hallucinations for individuals with schizophrenia who experienced auditory hallucinations. PSYCHOSOCIAL INTERVENTIONS
  • Today, few believe that psychological factors cause people to have schizophrenia or that traditional psychotherapeutic approaches will cure them. Nevertheless, you will see that psychological methods have an important role.
  • Despite the great promise of drug treatment, the problems with ineffectiveness, inconsistent use, and relapse suggest that by themselves drugs may not be effective with many people
  • Psychological treatment (talking therapy) helps you live with schizophrenia and have the best possible quality of life.
  • For psychological treatment to work well, you need a good working relationship with your doctor or other therapist. You need to be able to trust them and stay hopeful about your recovery
  • Types of psychological treatment for schizophrenia include cognitive behavioural therapy (usually called CBT), psychoeducation and family psychoeducation.
  • It also involves social skills training. This type of instruction focuses on improving communication and social interactions
  • CBT aims to help you identify the thinking patterns that are causing you to have unwanted feelings and behaviour, and learn to change this thinking with more realistic and useful thoughts.
  • For example, you may be taught to recognise examples of delusional thinking. You may then receive help and advice about how to avoid acting on these thoughts.
  • CBT helps you:
  • Feel less distressed the psychotic experiences
  • Feel less depressed and anxious
  • Reduce alcohol and drug abuse
  • Deal with suicidal thoughts
  • Overcome feelings of hopelessness
  • During the 19th century, inpatient care involved “moral treatment,” which emphasized improving patients’ socialization, helping them establish routines for self-control, and showing them the value of work and religion
  • Gordon Paul and Robert Lentz conducted pioneering work in the 1970s at a mental health center in Illinois (Paul & Lentz, 1977). Borrowing from the behavioral approaches used by Ted

Ayllon and Nate Azrin (1968), Paul and Lentz designed an environment for inpatients that encouraged appropriate socialization, participation in group sessions, and self-care such as bed making while discouraging violent outbursts

  • They set up an elaborate token economy, in which residents could earn access to meals and small luxuries by behaving appropriately
  • This incentive system was combined with a full schedule of daily activities. Paul and Lentz compared the effectiveness of applied behavioral (or social learning) principles with traditional inpatient environments. In general, they found that patients who went through their program did better than others on social, self-care, and vocational skills, and more of them could be discharged from the hospital.
  • One of the more insidious effects of schizophrenia is its negative impact on a person’s ability to relate to other people. Although not as dramatic as hallucinations and delusions, problems with social skills can be the most visible impairment displayed by people with schizophrenia and can prevent them from getting and keeping jobs and making friends. Clinicians attempt to reteach social skills such as basic conversation, assertiveness, and relationship building to people with schizophrenia.
  • In addition to social skills, programs often teach a range of ways people can adapt to their disorder yet live in the community
  • Preliminary evidence indicates that this type of training may help prevent relapses by people with schizophrenia, although longer-term outcome research is needed to see how long the effects last
  • To address some obstacles to this much-desired maintenance, such programs combine skills training with the support of a multidisciplinary team that provides services directly in the community, which seems to reduce hospitalization FAMILY INTERVENTIONS
  • Your knowledge of psychosis and schizophrenia can help a friend or family member who has it.
  • Research shows that people with schizophrenia who have a strong support system do better than those without the encouragement of friends and family.
  • Many people with schizophrenia rely on family members for their care and support. While most family members are happy to help, caring for somebody with schizophrenia can place a strain on any family.
  • Family therapy is a way of helping you and your family cope better with your condition. It involves a series of informal meetings over a period of around 6 months.
  • Meetings may include:
  • discussing information about schizophrenia
  • exploring ways of supporting somebody with schizophrenia
  • deciding how to solve practical problems that can be caused by the symptoms of schizophrenia
  • families could be helped by learning to reduce their level of expressed emotion and whether this would result in fewer relapses and better overall functioning for people with schizophrenia. Several studies have addressed these issues in a variety of ways (Falloon et al., 1985; Hogarty et al., 1986, 1991), and behavioral family therapy has been used to teach the families of people with schizophrenia to be more supportive
  • Some people find expressing things in a non-verbal way through the arts can provide a new experience of schizophrenia and help them develop new ways of relating to others.
  • Arts therapies have been shown to alleviate the negative symptoms of schizophrenia in some people.