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Creative BioMart provides a range of native and recombinant nucleosomes with or without post-translational modifications, histone variants, and methylated DNA. Their high-quality products are suitable for various applications, including enzyme kinetic studies, inhibitor screening, and structural studies. The advantages of using Creative BioMart's nucleosomes include reliable quality, extensive applications, and cost-effectiveness.
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The nucleosome is a complex composed of DNA and four pairs of
histones (eight in total), including two groups of H2A and H2B dimers
and two groups of H3 and H4 dimers. And the H1 is responsible for
linking DNA between two nucleosomes.
Advantages of Our Nucleosomes:
Reliable quality & Broad source: High-quality native nucleosomes
purified from eukaryotic nuclei or ultra-pure recombinant nucleosomes
assembled in vitro.
Extensive applications: Our nucleosome is an important tool for
your in vitro chromatin assembly, the optimal choice for your epigenetic
modifying enzyme assay and small-molecule inhibitor screening, and
the ideal substrate to study structural changes induced by the histone
variants and histone mutations.
Cost-effective: Creative BioMart saves you precious time and effort by
providing pre-assembled nucleosomes with competitive prices.