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Refrodusting Cgelieds % Earle ents , DATE:_L_/__ (/ Estrous Cele : : ' In ¢ MOS — \vertebvater ( onee pe promotes ) ; ot puberty a fomate shoulk hy thre, : hattern I of ( dia htobogtbat, & bia sin boaie!l jek € imetuce lWecedbuere amor paptos neal U Chamged im ey yehyoctuctive beg Stern Pog f behavinyal, 4 Chamges in | female. O ese Changes ane cvmleol a ( ) Extrous Cycle. ne. & Chomaes shad Cyclic ¥ repeated 0 Over tiene, d Comventionatle, he Sequence of vents that, ocewy Uo bles too huceomile edtrerses termed Estrous eae O- So ty estrous / ty \ femole & fitgsally 2 pchologioatly Coriditioned Vreecote, tw! g mate Y & btructunret, ' Chamaes ocewy dn thers) female ot Gt & Customary to . we ay feriod A ena veceptinits, of tw fermi fet matting. eft Vestrud ov heat Us te Ktamallrd for thy Cyclic. hana aE Seco Bae .-< lenky Micoue © fentod of ~ esthus Gn most, of Olomestiz, rer both Senes reco Conth rniesty throughout the eat . U mtinuows breeders. Shese _amennats ane. eto Co Yegher spre B08 ( eneepty omen) breed ont clofinete, period . Hhese as I peasoneal —_ reetwrd. Curing a eae Over Be Positive... CE Scanned with OKEN Scanner - CACTHRY) OY ~ Conce eo a Ty ool am the 7 us * 07 heat aya 4 Evemyey? ¢ means . latin wore — ae Neath. tion @ emale Lor fool’ ConAfe LOU pore EsGruS bs @ ; wer estrous , when ovation in heat animal Aare be pout . extiod eo estrus» Shis — S_ - ae auvtng t Bean ak, intr ry is" anxoureol 4 thy Co ser me fovmttteot v only canes as pee | Suypes of U heat Oust Some clomestic _—_ anermat partientarty Cows % mares; oteanitonalley exhibit qucet heats Sbese amematls oma bow “all he omotpmicat & phlyriolanical changes ofa Cepia Vortndus imetuctifa ovulation j but te . bern receptivity Uiw lacking. jhe _geceet heat may I be v caused bey Y faittowes to secrete. y CST V09E 1S én CM cere nt: amount to bring det the erent ll response. Prout, © 10% rmarex soo quiet seat cluwyting March - Dprel- U Spud heat: 9t is chsewed im Cows | panes. 7 She, initcal period of receptivity imtemupted by a period of Ono T U T , / weep, [ome w tao lags te meng few cla in cows) & Nts fothower by ampthey © period of heat, oy l nec, nite! Post, pontium | healt: femates of | sevdlar pees Come __im heart, Aho tig a 34 ~ BdPhitive.. CE Scanned with OKEN Scanner e) Duanéetomised feel inpecat E_ estrogen = Ye) ed Duvation of heat, tm. Some _antrmatt Name ¢ length of Heat, Jeme of ouutation animal, cee | per too [ o Mere 19- 29) clays 4-4 lores One ola, befeve ev one ola, 7 a atte 9 rrale if eo Cow 2) clays 13-12 hours | 19-15 hours after the end v of beat: o Goat 1G lays 39 hours [9114 tours after the y stort of U beat: id Gunes 16 clans 6-1 hours foc hours ! after the fa {| _* Hart of baat oe Yamstay 4 days 20 bours B-12 hours often the C stant of | beat eo Mouse! | 4 days 10 bours 2-3 hours! aftix thy v Start of V beat e Rar Y- 5 obs | 13-15 hours | C-l0 hours | alter the v stant of Utgag. «Dos 2 heat year | $-9 days | 1-3 days! alter te U vo ¢ v stane $ ah Oetuae : q _ wget Cat, || | 15-2 days G- to beurs| 24 hours afeer ott => Different. fasted of estrous Cucle. = SHEE Stockard & Papamicolon ((91#) working om Rots Cjpuen ea fas prover! wot, Y Be Positive.. CE Scanned with OKEN Scanner DATE:__/_/ _ | — Lvagénat, epithelivl at ahold bea p trois we 2Oyete, _feltowed] Wateuvathey ts, | io PERO nh of vaginal’ Ameo: U U Srastitionatiyn | tay U estrous epte bs oltvictest tmto ( pUow ima, bo ases (i i) Pro estrus I (i I : ii) |p CKtras. \ Gi)||_ Metaestrus w) Deerstris Proestruss 96 Chavactenixed bg omar heot imeem, in aativityy of vefrotdtive mystem: Shore 3 OvOxCOm U follibulon arrow th & g rexpacerepetiliiae, f regression | of CoWbus Lutenrn of 9 thy prewins exetle. Soe! uteres — & | vagina, enlarges Cpeghtt, ; the = emclormmet- rte becomes © Comaested” Uy edematous , te vaginal ILULOS A. U becomes lagpormic Kap Plotefevation Caused be, ‘estrogen _ seevet eof be, | omatune __folticres. VY She vanthat PY és Us.g im frockstvus frote U. Estrus — phase: This 5 ato ten as porto of heats Tom this Phase the ertyogen eevets! | ane tmcrecsed too | muh » This iy tL fevine of aceeftame . of tee male im_f the Johate usalley KeRALS about, the mate Ue stand V4y him to mate bev. The uterime , Comceat! 4% vaginal _4famels Aeevete imerveated amounts g of ee , the vaginal epitelium si emalobinttinderis, Be Positive... “TET CE Scanned with OKEN Scanner DATE:__/__/__ | Vearversesx at Sich he ea of ctiestrees, gn U 7 ; _ Ymonoestru< Apectes oestrus ts _follnwenp tous a peviool 4& s os | Cenestncs| of —_Aeaale imootivitly Ye So ints Onettys ts defimed as th et ) rvolonageo} : i ee footed taal nee ang genitar | Kg Stem is _amaimly ae queisceent. Ibe Y totticutar! development Vis * mentmak —, the / Corhora Luted ( otthough identifecarle ) Layee realestec} & gv fon 1 Are wm ~ etionatl), Seeretions O ane searky — & tenakinur, thy town ts Comsttnieted kt vagimal T TRULOSR da pore - I > Vaginal, changes curing ewvstrours eee IE vasimat 9 ehitretdim ceoowmt Uremain | Constant, / aAuwrimg I he entyous Cyete: In te amestrus phase ftw vanimat 4 efitnetium Chamae4 l kero ich v stratifecol AGUarmoOlys tpell te Uar.. thin vow cobdopar V ebeenel-_ bean: In liertrurs frase, _ epetlelirun yemalmk _ 9->>. Lagned lenteh ow | 5 made uf of cuboidal V Celh & loose Atyroma exit. he vasimat anULUA & Abkalone ottering ws but becomes aeretic im Y est | phase. 3 |! Uterine __ changes tewring estrous eel The estrogen stimutate ee ——_atedline Omctometrilim & it resembles __ to __ Sus Ll] etreese Thus eftert, 5 elm as Seuss Chtese effect» i a During ettys | the aterus i) Conaested > LI endohetwvem 5 Abupied — —-endlomatous fluich / I Be Positive... CE Scanned with OKEN Scanner DATE:_| J ’ is Contract? UtEVrs eke eile 5 the omeyewlanis of Cowieat —_chamges tui estrous _ tzele eeleter During ostrlls,, tue Y comin 4 ee time _ of ouulation L, Shore oceters metahtastic] Chamaes & teeyatimtration of enthoun Crete j Convdcat, ebithebinrm turing Sew Atroma | becomer bse oJ vas sett oti un wveases & munuerlatire atio » inert . Ovel ation . Ovetation usetathey oeeey& oliwytra, estrus: Put im few sheetos it eceeeds AlriovALy after we Y end of estes: During estrus, encourages / preg uemd matting 4 én Crease a Clathy eens of a! Spero ] to fertitixe thy Ova, Endocrine Conkmt of estrous ee ehe The Cy ehew chanbes that Y OCeLLy im Ow female g reprmocteretiveU track One emitiated a [ regulated ‘4 the lLipothatamic — fitu- lam, - Ovantiomn (_uPo) Casis . Altho folbtewtoreress _cuny tnedefondemttg of Bbome mbt Y stimnubation up aentit uw | dematiom of early, teritomy Yotlictes , tan aobastotro- tins" Luteimiding | hormone (tu) 0 folliete Stimulating Y\ trmone CRSH) > ane | . een tials fe Cae Commbtetion of) fol Ldertay moatimation 4 dwelotrrent | of (eatin fremuctation (frapion ) fetus: levels Be Positive.. CE Scanned with OKEN Scanner DATE:_| | _ Ovelation Lutetnisation gramutosa, hee thy UV ésiuttimg im Copultation ime exstru; Corpus g Cukem 5 7 cabeses Vagimocervital A > le ty. Athena tion agers thy weteass, of protartin > & . Ui amatntalms try Corpus Late | in a fumetionstl HLL» prolonging Ooluestrrus. Sher tonti- Chun rued _seevetioy U of prolonged tiase proge front DAS the v enolometatum em Blam bation of the thy maak cetels | —» Bech of | Abkmole | q IN Be Positive.. CE Scanned with OKEN Scanner | Menstrual cele, DATE:_/_/_ [ e.| Mat __ ders in primieites sola cn Gs —_ he eg etleal, | discharge, ofl! Eitbcoh', mmenetrs —] —_ certain cs subastbonceds from thy po us in thw reproductive OQ ete of a. fret at am auerege interval Vos lag icons AY~ 32 alags J} nstgeien Cote — onemptmind bregese 4 h he, Lengn of the egele vated constofevobky. Y oe am Quevelge, it tates 26 days (ay 30 cs) (7 ppKinkoge ¢ Mermot women. Memstiviatind U i. a ferinctical fiamdmenon that Continues —_ from puberty te! _onemopause She, fers memstr bbe dovtog 0 ilar stantp two U goa Oftey bobasts X plibec thaLy stant Vt U develop. with the » | advametng ' age of women 5 nw Ovaries become umrasspo-4 atte ‘itn gonadotrophin 4 Bary loose toby function “aorta I Causing tnall KEXMAL euyebe U & elisecbbean OC uswetty Vat an aged _us-$5 yn), thes stage | of bax Ueope is bia! onemopassed 1 Composition : } Toe is mache ep of hleod stripped muscles ! of emclometrium > meres 2 Lemeoey tes & am! | | eemfortilered? ovuwrn. he anemystiverat U doce — & Comes 0 outs from de uterus clots promptly due tt the Urapid — fomation of fiaorin, © ie | alll adil [ool ind Deal Shu whole | fempose io! piepone a Kestarte eal Yor! the veeeption & . I Le Vv. aft omptomtatio of the foxtitired Quer. olqmamen, _takds fence U toe spoté ration] T rod Be Positive... CE Scanned with OKEN Scanner DATE:__/_/ Lertostervone = & then — mt - B - tran Lt a ais Ue emrame of t7 wv B- Preqestrone aie in minstrel eycte thie Cee feedodeh t we lantertor : o> () | ‘ pitaithna, wm | Lowey the Levels of FSU & t | Lesher Mheing roctueed. Bn cxeviptisn Des is U luring ovulation , bn csiznis Cazes One & eviticar V amount) of [t - B-estractiog | &% «proctuceeas 7 it provicles fositive feedback | to | amteriny fituiton,| to proctececop bnereares? . amounts of SH Vg tye! are veqeuived) tov ovulation Daltitionatle, Ein tha feothack negation 2 he Gramutos ow Y CUS proctiele / A SO U activin , © _imunin © | activate ESu TeLeane feom the anterior fituitor, » thus flay Via wow in _ubreql- lation d & clowregsstatib meehamifms: = || Phases —# Memstruak eyele —= C (Dil Fotccutay or __—sproltteyative phase 9t Kw the 4 phase of menstrual eyele ¢é OCLLLVSE, trisomy! das! 1 bola, ty, | nl cel on te aueraly cuvcdtion of “26 daw / Be Poditiveld CE Scanned with OKEN Scanner DATE:_L_|__ to tte eno , the bmeveasedd —— amounts of (F-B- estradiol wit prooluee negative feedback to the Anterior | C qe l ue. ferrfose of thes ‘phase & to Grow uterts. te emtommetntal | layer. | of we us. Dddhiteomall, wis Hose is) 50 ementing to cn hy are ent’ ther ts | frien netsbluct t fossibbe into | wal Spero. Deréng’ his dose wien Ltieles Legit te ™ ate, Graafcan fotlicter ig ore en 7 ovlitation. | oT | Ovulation: 9b aces om lay LY bey member » At the ema of g pro Udevatlue foue _, IP - B- estracddot, levers ard, hag to follicle maturation + Durie, “ents time ont VY - Be extradiot Arovictels. dositive feedh ack d merhamesm tox ESY x cu Boctiue- €ton. She beg eves! of Feu Ly prewnt Lertma mnis “time és | Cf LH - Surge. ( As a 0 yes, hey mature, jaa peas veteoseh rca bande, gust Nig of progettren e exthronen- Shesel ti lndinomes j ered ies SISGba20 -& Bparmtalons ces! taibhmet Be Pasitive.. CE Scanned with OKEN Scanner DATE:_[__ | —— has ww potential to _ get fertile. The t i é x tated Y Ovulation provecs i Ya fluxing gonadotvoh te haw brosies ( cal tay eevee O Jue eek veautation * ConXrotted chamges 4 ew T fottow the lLermores are Cmbortamt 4 tau | clevetbbrrent — # release 7 : of Laxton ooelte inte ther achoenat eterdine | sbviuctunres v } = Gonaclotirofim - releasing hormone ( neu) i a trobie | peptide OC hormone mace & seeretect! by | | aw bapptrabioriv * Gt a releasing g hormone Lat Btomuhotes the release! of FSU # ly from the Lmtovior filuitiam, | througn various UV GnRH pute U Hpreainemetdh low freguemey Em RU futies One ‘vedpomaiiee fov Urey heeretion| whereday Proareiies putses ane vevponsthhee doy & semtrenses U 4 —__fprogentrone! in face 4 ecstrood Fimatt,! ae "bow Levers an Lu" folowing " tee surge vevtanty lew ESH | proctulction tp Ye sheow futsatir Atti ates d thy / growth & maturation toyymatinre fottlete+ v imtoo mature (gesps] second ang lice hefore ovulation, Be Positive... CE Scanned with OKEN Scanner | DATE:_/_/__ [ FSH Causes tee release. of etrogen trom thy —qpemetosen cells hot, T cero ean’ deletobina Qvantian follicles She, estroge, bs nevcfec! “Ves mn BE are th levetoberg Clommimant —_folbinter . ous, Zs estrogen v levets _veath_ a | erdticak | devel aw 00 ¢ mature iis hw dba : aD feefaration ‘fox ovelation , estrogen d (" eels porsistives | fesdnaek om UA Ynretion | leading to UH Surge. Sow LH createls the envink = ent tox fe Luielitox tab&ion ineveasin the betiviti, of frctsotger—! emepmes aot weakem § wel Ovonkan " attow Ema the fasfase of the O00 Ee + Adttex ue FF Oouyte és | L > . fottichitan nemmanthl Ore La teeth 4% Letotmenbol granulosa Cols . Sheeby dumetion ( &s to Prichiwen, progesterone , & les the bormone sesponntte | U fy maimtaiming the _, uterine emudvonment tbat Cam Vacece, i a fertitinedf embreo- : ba oe Follicutor fiste _ Lateat feats ee Lo ws . — Zen X Reo, \ PEL X 12346 6% @F mH 2 13 IY 15 6 14 2091 9) 9% 94 oF bry 18 a ——— LL / ee Mens Crus ton Protvfeyative. - Seexvetors foase Ovuta Linn Be Podlive... CE Scanned with OKEN Scanner DATE: | [_ I of gene promoters of _ afofptost5 <5 aeonene lt> © pnp! eatotines |, | vival oats froteins , ov Sere withdrawal of ecete prowth factors: v Se! initiation , _exeeution _& meg ation of apes tos imvotve vartous hiocheméicdL actors the Caspase famity of enkummes flay a Central U votell én | the vd apofto sts 0. signating « networr, Caspeses ane members! of Cae CO hegre, conkexvect dam ie of eg atitine proteasss & aspartate, sport fecitg. | Casparels Vo eure ertremeop ads fro- ig Zz io) at wnd tyeo 1 : proteolytic frocessing WO generate Gow lactivalel tom Valter af ptotic \ Ktimnuters. vhore axe..\! ty tapos of ‘caspases ictemttfcocf as "caspase! iio Fey. Some onembor of the ft aries. fumetion _ Apectalh, in Cettutdy death U a, U Vapoptones r_ 0 are subolty édeof énto @ imitintdy! Caspases Z 6.9 & w) ¥ executor ov efpectov caspases ( \ carfase 3,6 4 7). Exprestébn of caspase - 3 has heen foumel | Ovantalyl Leckhoe tes & a) fotticutay cots of atyetie! follicles. U Initiator caspalses are cleaelt &m seb pees to sft the Akeamrhe 4 actuate he efeete| During afohtorts 3 the ety eto | cated cleauds hadumetenia us Avotiidy located | im thy Coke imemrbromes, | meleus & eto dam: She activation of canpasene activatieof T pWase (cad) t fasihitater OND kepradation i Be Positive. CE Scanned with OKEN Scanner |v Thor, ave two ‘A DATE:_L_/__ [| One of the tenportant [unetlong whimiadiaca ls toy Canpases in. bisa) ae Aeotle fret maim | efeptotie| fats ; ays + S a the ertremsic oy death yeceftoy (etna 4a” the imbrensic Oy mbto chondrial I pation U = rE hese two pashwvays ave Limbo! % U the \" moleeles & One g pathwary Cam imftuenee ee omen, geal fatbaing tg thltiated tye eteawane of | caspllse = 3 & POSES th DA pradmontatlon , _blegvasfation of CytoMuletar Uy murcteay _ prteins F erosd = Con 3 eng oh proteins dorlation of apoptotic _ | tooie® | exhresion of | teganas | dow | phanoeytic cell __yeeeptoks aU imal, apeake, lag <4 toageigtion — te a ¢ r O 0 Cae. Extrensic _afoftotic, fatwa. Cous activate! | extremsee Qpoprotic ; t machinery, i» response to jeuyak Conctitions 3 searhaloms, Crroegh ahoftosis - velateo! memby- ane\.. & yecelbtors wo Ue serch apohtotie menace alter _timeling to —‘thain —respectine cour dealt U ergamets: U She extrenie potions Cam be inalecd tay members of tlle “TNE family | oh tutotur receptors 13 THER, , Fas UDas4 Tear 5 Des. | hese proteins Yeeruelt ae Ba ay toe 4 fro spate. 6 adebton proteins 3 Fann! , TRADD. these aap | protiins thm timo to de aetiiamd Se cealt reset > ferent thy eath - imolucing Atgnating Me prise) resulting of Be Positive.., CE Scanned with OKEN Scanner 
