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Lecture Exam 5 Study Guide
- TOPICS: The Lymphatic System and The Digestive System
What is the Lymphatic System?
- The lymphatic system is a series
of vessels , ducts, and trunks that remove interstitial fluid from the tissues and return it the blood.
Functions of the lymphatic
system
- Carries excess fluids to the
bloodstream
- Filters pathogens from the blood
- Lymph nodes swell during an
infection
- Transports immune cells (white
blood cells or lymphocytes)
Lymphatic System – Fluid Transport
- A major function of the lymphatic system is to drain body fluids and return them to the bloodstream. - Blood pressure causes leakage of fluid from the capillaries, resulting in the accumulation of fluid in the interstitial space. - Once this filtrate is out of the bloodstream and in the tissue spaces, it is referred to as interstitial fluid.
Functions of
the Lymphatic
System
~20 liters of fluid (plasma) diffuses
out of the blood vessels at the level
of the capillaries
~17 liters of this interstitial fluid is
reabsorbed directly by the blood
vessels.
~3 liters is brought back to the
blood vessels through lymphatic
vessels - via a series of vessels,
trunks, and ducts.
Primary lymphoid organs
- Primary lymphoid organs include:
- the bone marrow
- The thymus gland
- The bone marrow and thymus are the locations where lymphocytes of the adaptive immune system proliferate and mature.
lymphatic fluid
fluid is the term used
to describe interstitial
fluid once it has
entered the lymphatic
system.
Lymphatic Capillaries
- lymph is not actively pumped by the heart
- lymph is forced through the vessels by… - the movements of the body- the contraction of skeletal muscles during body movements, and breathing. - One-way valves (semi-lunar valves) in lymphatic vessels keep the lymph moving toward the heart.
Lymphatic Capillaries
- Lymphatic capillaries, also called the terminal lymphatics, are vessels where interstitial fluid enters the lymphatic system to become lymph fluid.
- Lymphatic capillaries are interlaced among the arterioles and venules of the circulatory system in the soft connective tissues of the body.
lacteals
- In the small intestine, lymphatic
capillaries called lacteals are critical for
the transport of dietary lipids and lipid-
soluble vitamins to the bloodstream.
- In the small intestine, dietary
triglycerides combine with other lipids
and proteins, and enter the lacteals to
form a milky fluid called chyle.
- The chyle then travels through the
lymphatic system, eventually entering
the liver and then the bloodstream.
lymph nodes
- Cells of the immune system also use lymph nodes as major staging areas for the development of critical immune responses.
- A lymph node is one of the small, bean-shaped organs located throughout the lymphatic system.
Lymphatic Vessels
- The lymphatic vessels begin as capillaries, which feed into larger and larger lymphatic vessels, and eventually empty into the bloodstream by a series of ducts.