Ggghgfdddddddeeeeeeeeeeee, Schematy z Filozofia

Pobierz Ggghgfdddddddeeeeeeeeeeee i więcej Schematy w PDF z Filozofia tylko na Docsity!

PATHOLOGY OF PREGNANCY

Dr. Melinda Hajdu

1st Dept of Pathology and Experimental

Cancer Research

April 23, 2020

INFLAMMATIONS Vulvitis Vaginitis Cervicitis allergic contact dermatitis irritative contact dermatitis

• Human papillomavirus
• Herpes simplex virus-1/
• Neisseria gonorrhoeae
• Treponema pallidum
• Candida spp.
  • Candida albicans
  • Trichomonas vaginalis
  • Bacterial vaginosis
    • Chlamydia trachomatis
    • Neisseria gonorrhoeae
    • Ureaplasma urealyticum
    • Trichomonas vaginalis
    • Escherichia coli
    • Candida spp.
    • Streptococcusok
    • Herpes simplex virus- 2

Pelvic inflammatory disease

Infertility

Ascending infections in pregnancy

Bartholin-cyst Bartholin-abscess https://images.emedicinehealth.com/images/4453/4453- 13248 - 20055 - 51340.jpg

TUBO-OVARIAN ABSCESS https://webpath.med.utah.edu/jpeg4/FEM041.jpg Pathologyoutlines.com https://www.memorangapp.com/flashcards/238136/4b+-+Ovary+and+Fallopian+Tubes/

Actinomycosis

ECTOPIC PREGNANCY http://library.med.utah.edu/WebPath/jpeg4/FEM132.jpg https://obgynkey.com/wp-content/uploads/2017/02/00301.jpeg 25/1000 pregnancies

• Fallopian tube (90%)
• Ovary
• Abdominal cavity
• Cervix
• Scar of cesarean section Risk factors
  • Salpingitis/pelvic inflammatory disease
  • Previous abdominal/pelvic surgery
  • Endometriosis
  • Previous ectopic pregnancy
  • Tubal ligation

INFLAMMATIONS/INFECTIONS OF THE PLACENTA https://librepathology.org/w/images/thumb/9/94/Chorioamnioni tis_- 2 - very_high_mag.jpg/300px-Chorioamnionitis- 2 - _very_high_mag.jpg Hematogenous infections Listeria monocytogenes Tuberculosis Syphilis To xoplasma R ubella C ytomegalovirus H erpes Premature rupture of the membranes Complications

• Chorioamnionitis
• Funisitis
• Villitis
• Neonatal sepsis Ascending infections Mycoplasma hominis Ureaplasma urealyticum Streptococcus agalactiae Candida Vaginal/enteral flora http://www.webpathology.com/slides-13/slides/Placenta_AcuteVillitis3.jpg Chorioamnionitis Villitis

Pre-eclampsia

Hypertension (>140/>90 Hgmm)

Proteinuria

Edema

• Impaired kidney function
• Impaired liver function
• Thrombocytopenia
• Headache, visual disturbances

Risk factors

• Hypertension
• Diabetes mellitus
• Obesity
• First pregnancy
• Previous pre-eclampsia
• Multiple pregnancy

Eclampsia

Seizures following pre-eclampsia

HELLP-syndrome

• Hemolysis
• Elevated Liver enzymes
• Low Platelet count
• Abdominal pain
• Headache
• Nausea, vomiting

Complications

• DIC
• Liver failure, hemorrhage,

rupture

• Renal insufficiency
• Lung edema
• Cerebral hemorrhage GESTATIONAL HYPERTENSIVE DISEASES

GESTATIONAL TROPHOBLASTIC DISEASES

Hydatidiform mole

• Partial
• Complete

Gestational choriocarcinoma

Placental Site Trophoblastic Tumor (PSTT)

HYDATIDIFORM MOLE Partial mole Complete mole Karyotype hCG Risk of choriocarcinoma

http://freepregnancytest.net/wp-content/uploads/2018/02/using-ultrasounds-safe.png

69,XXY (XXX, XYY) 46,XX (XY)

Embryo/fetus yes (abnormal) none 46XX 46XX 46XY duplication 23X 69XXY 69XXX 69XYY 23X 23X 23X 23X 23Y 23Y 23Y 23Y 23X 23X 23X empty ovum

GESTATIONAL CHORIOCARCINOMA http://peir.path.uab.edu/library/_data/i/upload/2013/08/01/20130801094138-7116b454-me.jpg

• complete mole (50%)
• abortion (25%)
• normal pregnancy (25%) preceded by more frequent in Asian and African women responds well to chemotherapy (NOT ovarian/testicular choriocarcinoma!)

THANK YOU FOR YOUR

ATTENTION!