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Blood Typing and the Importance of Compatibility in Blood Transfusions, Study Guides, Projects, Research of Genetics

University of Pennsylvania (UPenn)Genetics

The concept of blood typing based on abo and rh blood groups, and the importance of ensuring compatibility between donor and recipient blood types during transfusions to prevent adverse reactions. It covers the genetics of blood types, antigens and antibodies, and the potential consequences of transfusing incompatible blood.

Typology: Study Guides, Projects, Research

2021/2022

Uploaded on 09/27/2022

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jamal33 🇺🇸

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Cardiovascular System Activity #2 page 1
BIOLOGY II NAME_____________________
CARDIOVASCULAR SYSTEM
ACTIVITY #2 DATE__________HOUR______
BLOOD TYPING
OBJECTIVE:
5. Explain how blood is typed and why it is important to type blood. (pp. 340 –
343)
ABO BLOOD GROUPS
BLOOD TYPE GENETICS BLOOD
A
IAIA
or
IAi
B
IBIB
or
IBi
AB IAIB
O ii
I
A
= allele for antigen A
IB = allele for antigen B
i = allele for no antigen
Antigen A
Anti-B antibodies
Antigen B
Anti-A antibodies
Antigen A
Antigen B
No antibodies
No antigens
Anti-A antibodies
Anti-B antibodies
pf3

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BIOLOGY II NAME_____________________ CARDIOVASCULAR SYSTEM ACTIVITY #2 DATE__________HOUR______

BLOOD TYPING OBJECTIVE:

  1. Explain how blood is typed and why it is important to type blood. (pp. 340 –

ABO BLOOD GROUPS

BLOOD TYPE GENETICS BLOOD

A

IAIA

or IAi

B

IBIB

or IBi

AB IAIB

O ii

IA^ = allele for antigen A IB^ = allele for antigen B i = allele for no antigen

Antigen A Anti-B antibodies

Antigen B Anti-A antibodies

Antigen A Antigen B No antibodies

No antigens Anti-A antibodies Anti-B antibodies

Rh Factor

BLOOD TYPE GENETICS BLOOD

Rh+ RR or Rr

Rh- rr

RH-NEGATIVE BLOOD AFTER EXPOSURE TO RH-POSITIVE

BLOOD TYPE GENETICS BLOOD

Rh- rr

IMPORTANCE OF TYPING BLOOD

R = allele for Rh antigen r = allele for no antigen

Rh antigen

no antigen

No Rh antigen Anti-Rh antibodies

Type A blood given to Type B patient

Anti-A antibodies from patient attack antigen A RBCs in transfusion Result: clumping Blocked blood vessels Could result in death