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NUR 210 UNIT 9 STUDY GUIDE
TEST #3 โ€“ Endocrine Drugs
Chapter 49: Pituitary, Thyroid, Parathyroid & Adrenal Disorders
EXAM PRIORITIES
Know These 5 Drugs
Drug
Used For
Key Teaching
Levothyroxine
Hypothyroidism
Take on an empty
stomach
PTU
Hyperthyroidism
Report fever/sore throat
Calcitriol
Hypoparathyroidism
Raises calcium
Prednisone
Inflammation/Addison's
Never stop abruptly
Fludrocortisone
Addison's Disease
Monitor potassium
THYROID DISORDERS
HYPOTHYROIDISM
Memory Trick
LOW & SLOW
Signs & Symptoms
โ— Weight gain
โ— Fatigue
โ— Constipation
โ— Bradycardia
โ— Cold intolerance
โ— Dry skin
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pf4
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NUR 210 UNIT 9 STUDY GUIDE

TEST #3 โ€“ Endocrine Drugs

Chapter 49: Pituitary, Thyroid, Parathyroid & Adrenal Disorders

EXAM PRIORITIES

Know These 5 Drugs

Drug Used For Key Teaching

Levothyroxine Hypothyroidism Take on an empty stomach

PTU Hyperthyroidism Report fever/sore throat

Calcitriol Hypoparathyroidism Raises calcium

Prednisone Inflammation/Addison's Never stop abruptly

Fludrocortisone Addison's Disease Monitor potassium

THYROID DISORDERS

HYPOTHYROIDISM

Memory Trick

LOW & SLOW

Signs & Symptoms

โ— Weight gain โ— Fatigue โ— Constipation โ— Bradycardia โ— Cold intolerance โ— Dry skin

โ— Depression โ— Slow thinking

Labs

Lab Result

T3 Low

T4 Low

TSH High

Emergency

MYXEDEMA COMA

Symptoms

โ— Severe hypotension โ— Bradycardia โ— Respiratory depression โ— Altered LOC

Priority

โœ… Airway

โœ… Breathing

LEVOTHYROXINE (SYNTHROID)

Used For

Hypothyroidism

Action

โ— Replaces T3 and T โ— Increases metabolism

Signs & Symptoms

โ— Weight loss โ— Tachycardia โ— Diarrhea โ— Heat intolerance โ— Sweating โ— Anxiety โ— Goiter โ— Exophthalmos

Labs

Lab Result

T3 High

T4 High

TSH Low

Graves Disease

Classic Signs

๐Ÿ‘€ Exophthalmos (Bulging eyes)

๐Ÿฆ‹ Goiter

โค Tachycardia

๐Ÿ”ฅ Heat intolerance

THYROID STORM

MEDICAL EMERGENCY

Early Signs

โญ Agitation

โญ Confusion

Other Signs

โ— Fever โ— Severe hypertension โ— Severe tachycardia

Priority

Give antithyroid medications immediately

ANTITHYROID DRUGS

Propylthiouracil (PTU)

Used For

Hyperthyroidism

Graves Disease

Pregnancy

โญ Drug of choice in pregnancy

Side Effects

โ— Rash โ— Fever โ— Sore throat

NCLEX ALERT

Report:

โœ… Fever

โœ… Sore throat

May indicate:

โญ Agranulocytosis

Function:

Controls blood calcium levels

NORMAL CALCIUM

โœ… 9.0 โ€“ 10.5 mg/dL

Above 10.5 = Hypercalcemia

Below 9.0 = Hypocalcemia

HYPERPARATHYROIDISM

Too Much PTH

Result:

โฌ† Calcium

(Hypercalcemia)

Memory

STONES, MOANS, GROANS

Symptoms

๐Ÿชจ Kidney Stones

๐Ÿฆด Bone Fractures

๐Ÿ’ฉ Constipation

Treatment

Goal:

Lower Calcium

โ— IV Furosemide

โ— IV Saline โ— IV Phosphate โ— Parathyroidectomy

HYPOPARATHYROIDISM

Too Little PTH

Result:

โฌ‡ Calcium

(Hypocalcemia)

Causes

โญ Thyroidectomy

โญ Low Magnesium

โญ Autoimmune Disease

โญ Radiation

Signs

LOW CALCIUM = TWITCHY

Chvostek Sign

Tap cheek

Positive = facial twitch

Trousseau Sign

Inflate BP cuff

Positive = hand spasm

Functions :

โ— Raises glucose โ— Reduces inflammation โ— Stress response

Aldosterone

Functions:

โ— Retains sodium โ— Retains water โ— Excretes potassium

ADDISON DISEASE

LOW CORTISOL

LOW ALDOSTERONE

Symptoms

โ— Fatigue โ— Weakness โ— Weight loss โ— Hypotension

CUSHING SYNDROME

TOO MUCH CORTISOL

Symptoms

๐ŸŒ Moon Face

๐Ÿƒ Buffalo Hump

โฌ† BP

โฌ† Glucose

๐Ÿฆด Osteoporosis

๐Ÿฉธ Easy Bruising

PREDNISONE

MOST TESTED ADRENAL DRUG

Uses

โ— Asthma โ— Inflammation โ— Autoimmune disease โ— Organ transplant

Side Effects

Think :

CUSHING SYNDROME

โ— Moon face โ— Weight gain โ— Hyperglycemia โ— Hypertension โ— Fluid retention โ— Osteoporosis

Nursing Teaching

MUST KNOW

โŒ Never stop abruptly

Can cause:

โญ Adrenal Crisis

Take with food

Avoid sick people