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Lipids Classification Structure Functions
Typology: Study notes
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Lipids may be either liquids or non-crystalline solids at room temperature. Pure fats and oils are colorless, odorless, and tasteless. They are energy-rich organic molecules Insoluble in water Soluble in organic solvents like alcohol, chloroform, acetone, benzene, etc. No ionic charges Solid triglycerols (Fats) have high proportions of saturated fatty acids. Liquid triglycerols (Oils) have high proportions of unsaturated fatty acids.
Lipids are made of the elements Carbon, Hydrogen and Oxygen, but have a much lower proportion of water than other molecules such as carbohydrates. Unlike polysaccharides and proteins, lipids are not polymers— they lack a repeating monomeric unit. They are made from two molecules: Glycerol and Fatty Acids. A glycerol molecule is made up of three carbon atoms with a hydroxyl group attached to it and hydrogen atoms occupying the remaining positions. Fatty acids consist of an acid group at one end of the molecule and a hydrocarbon chain, which is usually denoted by the letter ‘R’. They may be saturated or unsaturated. A fatty acid is saturated if every possible bond is made with a Hydrogen atom, such that there exist no C=C bonds.
Unsaturated fatty acids, on the other hand, do contain C=C bonds. Monounsaturated fatty acids have one C=C bond, and polyunsaturated have more than one C=C bond
Lipids can be classified according to their hydrolysis products and according to similarities in their molecular structures. Three major subclasses are recognized:
(a) Fats and oils which yield fatty acids and glycerol upon hydrolysis. (b) Waxes , which yield fatty acids and long-chain alcohols upon hydrolysis Fats and Oils Both types of compounds are called triacylglycerols because they are esters composed of three fatty acids joined to glycerol, trihydroxy alcohol. The difference is on the basis of their physical states at room temperature. It is customary to call a lipid a fat if it is solid at 25°C, and oil if it is a liquid at the same temperature. These differences in melting points reflect differences in the degree of unsaturation of the constituent fatty acids. Waxes Wax is an ester of long-chain alcohol (usually mono-hydroxy) and a fatty acid. The acids and alcohols normally found in waxes have chains of the order of 12-34 carbon atoms in length.
(a) Phospholipids , which yield fatty acids, glycerol, amino alcohol sphingosine, phosphoric acid and nitrogen-containing alcohol upon hydrolysis. They may be glycerophospholipids or sphingophospholipid depending upon the alcohol group present (glycerol or sphingosine). (b) Glycolipids , which yield fatty acids, sphingosine or glycerol, and a carbohydrate upon hydrolysis. They may also be glyceroglycolipids or sphingoglycolipid depending upon the alcohol group present (glycerol or sphingosine).