Lipids - clarification,functions, Study notes of Biochemistry

Lipids Classification Structure Functions

Typology: Study notes

2022/2023

Uploaded on 03/04/2023

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Lipids definition
• Lipids are a heterogeneous group of organic compounds that are
insoluble in water and soluble in non-polar organic solvents.
•They naturally occur in most plants, animals, microorganisms and
are used as cell membrane components, energy storage molecules,
insulation, and hormones.
Properties of Lipids
Lipids may be either liquids or non-crystalline solids at room
temperature.
Pure fats and oils are colorless, odorless, and tasteless.
They are energy-rich organic molecules
Insoluble in water
Soluble in organic solvents like alcohol, chloroform, acetone,
benzene, etc.
No ionic charges
Solid triglycerols (Fats) have high proportions of saturated fatty
acids.
Liquid triglycerols (Oils) have high proportions of unsaturated
fatty acids.
Structure of Lipids
Lipids are made of the
elements(Carbon,(Hydrogen(and(Oxygen, but have a much
lower proportion of water than other molecules such
as(carbohydrates.(
Unlike polysaccharides and proteins, lipids are not polymers—
they lack a repeating monomeric unit.
They are made from two molecules:(GlycerolandFatty
Acids.
A glycerol molecule is made up of three carbon atoms with a
hydroxyl group attached to it and hydrogen atoms occupying
the remaining positions.
Fatty acids consist of an(acid group(at one end of the molecule
and a hydrocarbon chain, which is usually denoted by the
letter ‘R’.
They may be(saturatedorunsaturated.
A fatty acid is saturated if every possible bond is made with a
Hydrogen atom, such that there exist no C=C bonds.
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Lipids definition

  • Lipids are a heterogeneous group of organic compounds that are insoluble in water and soluble in non-polar organic solvents. •They naturally occur in most plants, animals, microorganisms and are used as cell membrane components, energy storage molecules, insulation, and hormones.

Properties of Lipids

 Lipids may be either liquids or non-crystalline solids at room temperature.  Pure fats and oils are colorless, odorless, and tasteless.  They are energy-rich organic molecules  Insoluble in water  Soluble in organic solvents like alcohol, chloroform, acetone, benzene, etc.  No ionic charges  Solid triglycerols (Fats) have high proportions of saturated fatty acids.  Liquid triglycerols (Oils) have high proportions of unsaturated fatty acids.

Structure of Lipids

 Lipids are made of the elements Carbon, Hydrogen and Oxygen, but have a much lower proportion of water than other molecules such as carbohydrates.  Unlike polysaccharides and proteins, lipids are not polymers— they lack a repeating monomeric unit.  They are made from two molecules: Glycerol and Fatty Acids.  A glycerol molecule is made up of three carbon atoms with a hydroxyl group attached to it and hydrogen atoms occupying the remaining positions.  Fatty acids consist of an acid group at one end of the molecule and a hydrocarbon chain, which is usually denoted by the letter ‘R’.  They may be saturated or unsaturated.  A fatty acid is saturated if every possible bond is made with a Hydrogen atom, such that there exist no C=C bonds.

 Unsaturated fatty acids, on the other hand, do contain C=C bonds. Monounsaturated fatty acids have one C=C bond, and polyunsaturated have more than one C=C bond

Classification (Types) of Lipids

Lipids can be classified according to their hydrolysis products and according to similarities in their molecular structures. Three major subclasses are recognized:

1. Simple lipids

(a) Fats and oils which yield fatty acids and glycerol upon hydrolysis. (b) Waxes , which yield fatty acids and long-chain alcohols upon hydrolysis Fats and Oils  Both types of compounds are called triacylglycerols because they are esters composed of three fatty acids joined to glycerol, trihydroxy alcohol.  The difference is on the basis of their physical states at room temperature. It is customary to call a lipid a fat if it is solid at 25°C, and oil if it is a liquid at the same temperature.  These differences in melting points reflect differences in the degree of unsaturation of the constituent fatty acids. Waxes  Wax is an ester of long-chain alcohol (usually mono-hydroxy) and a fatty acid.  The acids and alcohols normally found in waxes have chains of the order of 12-34 carbon atoms in length.

2. Compound lipids

(a) Phospholipids , which yield fatty acids, glycerol, amino alcohol sphingosine, phosphoric acid and nitrogen-containing alcohol upon hydrolysis. They may be glycerophospholipids or sphingophospholipid depending upon the alcohol group present (glycerol or sphingosine). (b) Glycolipids , which yield fatty acids, sphingosine or glycerol, and a carbohydrate upon hydrolysis. They may also be glyceroglycolipids or sphingoglycolipid depending upon the alcohol group present (glycerol or sphingosine).