NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE, Exams of Nursing

NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE

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NSG 550 Diagnostics Study Guide Quiz 1 LATEST GUIDE
Diagnostic Reasoning Study Guide - Quiz 1
Clinical Reasoning
o Knowledge + cognition = metacognition
o Collect H&P, complete physical exam, interpret diagnostic studies
o Clinical decision making is multifaceted and encompasses the patient, clinical
problem, and the practitioner’s perspectives.
o Critical thinking involves application of analysis, evaluation, and inference
o Accuracy: does the test measure what it was designed to measure; proportion of
all tests (positive and negative) that are correct.
o Precision: does the test reproduce the same results when repeated on the same
patient or a sample; a test can be precise but not necessarily accurate if the results
differ from reference range.
o Sensitivity: among people who have the disease, how often is the test right?
o Specificity: among people who do not have the disease, how often is the test
right?
Patient follow-up with results
o Do not give over the phone, or on answering machine
o Do not give to family/friends unless written consent is given
o Provide education on meaning of results, disease process, home care, next visit,
and treatment options
American College of Radiology (ACR) Appropriateness Criteria
o Evidence-based guidelines to assist referring physicians and other providers
in making the most appropriate imaging or treatment decision for a specific
clinical condition
o Starting January 2020 the ACR Appropriateness Criteria used by health care
providers for determining imaging studies for patient management will
become the standard of care for reporting on Medicare patients.
ACR Practice Guidelines for Communication of Diagnostic Imaging Findings
o Effective communication should 1) promote optimal patient care and support
the referring physician/health care provider in this endeavor, 2) be tailored to
satisfy the need for timeliness, and 3) minimize the risk of communication
errors.
Examples of Various Diagnostic Studies
Blood studies
o Used to establish Dx, r/o clinical problem, monitor therapy, establish prognosis,
screen for disease
o Venous most common
o Arterial causes more discomfort, used for blood gasses, higher risk of hematoma
hold pressure longer
o skin puncture often used in pediatrics, mix of venous and arterial. Earlobe can
be used for arterial if needed. Do not milk d/t hemolysis
Electrodiagnostic studies
o Tests electrical impulses
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Diagnostic Reasoning Study Guide - Quiz 1

- Clinical Reasoning o Knowledge + cognition = metacognition o Collect H&P, complete physical exam, interpret diagnostic studies o Clinical decision making is multifaceted and encompasses the patient, clinical problem, and the practitioner’s perspectives. o Critical thinking involves application of analysis, evaluation, and inference o Accuracy: does the test measure what it was designed to measure; proportion of all tests (positive and negative) that are correct. o Precision: does the test reproduce the same results when repeated on the same patient or a sample; a test can be precise but not necessarily accurate if the results differ from reference range. o Sensitivity: among people who have the disease, how often is the test right? o Specificity: among people who do not have the disease, how often is the test right?

  • Patient follow-up with results o Do not give over the phone, or on answering machine o Do not give to family/friends unless written consent is given o Provide education on meaning of results, disease process, home care, next visit, and treatment options - American College of Radiology (ACR) Appropriateness Criteria o Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for a specific clinical condition o Starting January 2020 the ACR Appropriateness Criteria used by health care providers for determining imaging studies for patient management will **become the standard of care for reporting on Medicare patients.
  • ACR Practice Guidelines for Communication of Diagnostic Imaging Findings** o Effective communication should 1) promote optimal patient care and support the referring physician/health care provider in this endeavor, 2) be tailored to satisfy the need for timeliness, and 3) minimize the risk of communication errors. Examples of Various Diagnostic Studies
  • Blood studies o Used to establish Dx, r/o clinical problem, monitor therapy, establish prognosis, screen for disease o Venous – most common o Arterial – causes more discomfort, used for blood gasses, higher risk of hematoma - hold pressure longer o skin puncture – often used in pediatrics, mix of venous and arterial. Earlobe can be used for arterial if needed. Do not milk d/t hemolysis
  • Electrodiagnostic studies o Tests electrical impulses

o May cause discomfort from stimulation o Do not move, have caffeine or sedatives before test o Few complications o Not invasive, usually do not need written consent

  • Endoscopy o Need written consent o Baseline labs o Prep depending on type of study o Like minor surgery (educate re: sedative, have emergency equipment available, need ride home) o IV antibiotics for those with prosthetic joints or cardiac valve disease o Education – may cause gas, discomfort, infection signs
  • Fluid Analysis Studies o Normal fluids and effusions o Aspiration must be sterile o Diagnostic and therapeutic o Risks: infection, seeding of malignancies, leakage, reflex bradycardia/hypotension from anxiety
  • Manometric Studies o Measure and record pressures
  • Microscopic Studies o Biopsy, culture/smear (STIs, TB, etc.), pathologic conditions (liver, renal, urological), PAP o Gram staining and shape (Gram neg rods = e coli)
  • Nuclear Scanning o Stage cancer, detect sites of GI bleed, diagnose cholecystitis/pulm embolism, brain scan, eval gastric emptying/thyroid nodules/testicular swelling/cardiac function o Technetium-99m (99mTc) is used extensively in nuclear scanning because its half-life is 6 hours and it emits low levels of gamma rays. Other commonly used radionuclides include gallium, thallium, and iodine. o Combined with a transport molecule that takes the radionuclide to the intended organ o Superimpose of baseline CT/PET to see hot and cold spots o Normally uptake is consistent across organ o SPECT gives 3D images o Radiation risk but less than x-rays o Contraindicated in pregnant and nursing o Use toilet and flush several times after use, clean up spilled urine, wash hand thoroughly, wash soiled clothes separately o Asses for allergy o Oral, inhaled or IV admins of radionuclide o Encourage water drinking
  • Stool tests

▪ Intermediate reaction (mouth/throat edema, bronchospasm, chest pain, chills/fever) Give antihistamines and maybe steroids, fluids, bronchodilators ▪ Severe reaction (edema, hypotension, MI, arrythmia, seizure, resp failure) Give antihistamines, steroids, fluids, bronchodilators, intubation/vent, pressors, antiepileptics ▪ Delayed reactions can occur for 2 - 6hrs

  • MRI o No radiation o Advantage over CT – better contrast image, no obscuring bone, natural blood vessel contrast, can image multiple angles o Evals most body systems – brain, GI, muscle, cardiac, breast, spine o Expensive and labor intensive o Can use contrast like gandolinium or gasoxetate ▪ Should check renal function, especially in those over age 60 o Contraindicated in extreme obesity, claustrophobia, agitation, metal in body o Remove patches and any metal, remain still Urologic/Renal
  • Imaging studies o KUB – not specific o Pyelography – mostly replaced with CT. ▪ X-ray that uses contrast injected into renal system or IV. ▪ Indicated for stones, hematuria, trauma, outlet obstruction, tumor, pelvic surgery o Renal scan ▪ Nuclear study - Radioisotope and scintillation camera ▪ No iodine, safe to use in renal disease and allergies ▪ Perfusion, structure, function, hypertension, or obstruction ▪ Not to be done w/I 24 hrs of IVP ▪ Evaluate transplant rejection o Cystoscopy ▪ Camera in bladder ▪ Used for hematuria, recurrent UTI, dysuria, frequency, retention, inadequate stream, urgency, incontinence ▪ Diagnostic
  • Ureter sample collection, visualization, measurement, calculi ▪ Therapeutic
  • Resection of tumors, removal of FB, dilation, stent placement, coag of bleeding, implant radium seeds, TURP ▪ Urethroscope, cystoscope, ureteroscope. Nephroscope ▪ Complications – perforation, sepsis, hematuria, retention ▪ Assess voiding for 24 hrs, note urine color (pink tinge common) avoid standing immediately after, burning during urination common (should pee

sitting), drink fluids, observe for sepsis, may use antibiotics before and after, avoid constipation ▪ Tumor, stones, prostate hypertrophy/cancer, inflammation, stricture

  • Interpreting a Urinalysis ▪ Appearance: clear - Cloudy d/t pus or foods (fat, urates, phosphates) ▪ Color: amber yellow - Kidney bleed- dark red - Lower bleed – bright red - Urobilinogen or bilirubin – dark yellow - Pseudomonas – green - Beets/rhubarb – red/brown ▪ Odor: aromatic - DKA – acetone - UTI – foul - Enterobladder fistula – fecal - PKU - musty ▪ pH: 4.6-8.0 (average, 6.0) - acid base balance, foods - acidic urine associated with zanthine, cystine, uric acid and calcium oxalate stones - alkaline urine associated with calcium carb/phos and mag phos stones. UTI - urine become alkaline on standing ▪ Protein: 0 – 8 mg/dL; 50– 80 mg/24 hr (at rest); <250 mg/24 hr (during exercise) - Presence indicates glomerular capsule injury - During pregnancy - preeclampsia - Proteinuria and edema – nephrotic syndrome - If random elevated, do 24 hr - Usually checked with creatinine - Orthostatic proteinuria ▪ Specific gravity: Adult: 1.005–1.030 (usually, 1.010–1.025) - Elderly: values decrease with age - Newborn: 1.001–1. - High means concentrated and low means dilute - SIADH – elevated SG - DI – decreased SG - Renal disease causes dilute - Easier to check than osmolality ▪ Leukocyte esterase : negative - Pos (>100,000) = UTI, contamination by vaginal secretions ▪ Nitrites: none - Pos = UTI ▪ Ketones: none

o Part of electrolyte studies o Regulated by kidneys o Increase = alkalosis o Decrease = acidosis (renal failure)

  • Testing to diagnose and manage CKD o Urine albumin o Serum Creatinine (0.5-1.2 mg/dl) ▪ >4 mg/dL (indicates serious impairment in renal function) ▪ Normal differs by sex, age: lower in children ▪ Trough at 7am, Peak at 7pm, ▪ Higher after meal ▪ Dehydration and diet high in meat causes elevation ▪ Increased: Diseases affecting renal function, such as glomerulonephritis, pyelonephritis, acute tubular necrosis, urinary tract obstruction, reduced renal blood flow (eg, shock, dehydration, congestive heart failure [CHF], atherosclerosis), diabetic nephropathy, nephritis. Also, rhabdo/increased muscle mass diseases ▪ Interpreted with BUN: BUN/Create ratio normally 6 - 25 (15.5 optimal) ▪ Used to estimate GFR o BUN (7-20) ▪ Formed in liver and excreted by kidney ▪ Low in liver disease, high in kidney disease o Creatinine Clearance ▪ 90 - 140, higher in males ▪ Decreases by 6.5 with each decade of age after 20 ▪ 24 hr urine and serum creatinine used to calculate ▪ Measure of GFR ▪ Decreased in kidney disease and anything that reduces kidney perfusion o eGFR ▪ Cystatin C might be better to estimate GFR than Create because its more stable ▪ Calculated by create/CC and age, gender, race ▪ Normal around 120 ▪ Below 60 indicates disease ▪ Below 15 is kidney failure Endocrine
  • Thyroid Nodule Diagnosis and Imaging o US can identify non palpable nodules and cysts – preferred method ▪ Malignant nodules are mostly solid and hypoechoic with irregular margins ▪ Benign nodules are well defined and hyperechoic o Scintigraphy reserved for characterizing functioning nodules and for staging follicular and papillary carcinomas o Plain radiographs are used to detect retrosternal thyroid extension, thyroid calcification, bony or mediastinal lymph nodes, and lung metastases. Limited usefulness

o CT scanning is an effective method for detecting regional and distant metastasis from thyroid cancer. o MRI has a limited role in characterizing thyroid nodules, although it appears to be effective in the diagnosis of cervical lymph node metastasis and staging cancers. o

  • Fine Needle Aspiration of Thyroid o Percutaneous needle aspiration remains the key procedure in the diagnosis of thyroid lymphoma; however, thyroid lymphoma's differentiation from thyroiditis occasionally can be difficult. A tissue-specific diagnosis of a lymphoma can be achieved by using US-guided FNA. o Risks – bleeding, infection, injury to vital structures, bruises o Might need to stop blood thinners o Results – benign (f/u), cancerous (remove), indeterminate (repeat in few months), inadequate (repeat in few months)
  • Thyroid function tests o TSH (0.3-5) ▪ Elevated – hypothyroid ▪ Decreased – hyperthyroid ▪ Trough 10am, peak 10pm o Thyroxine (T4) – 5 - 12, free 0.8-1.8 micrograms o Triiodothyronine (T3) – 100 - 200 nanograms
  • Diabetes o C-Peptide - evaluates islet cell function (0.5-2) ▪ Used to evaluate diabetic patients and to identify patients who secretly self-administer insulin. C-peptide is also helpful in monitoring patients with insulinomas ▪ Decreased in DM with insulin admin ▪ Usual correlates with insulin levels but more accurately reflects islet cell function in patients taking insulin o Fasting plasma glucose, a 75 - gram oral glucose tolerance test (also called the 2 - hour glucose tolerance test), and hemoglobin A1C are all valuable in diagnosing DM o Microalbumin – first indicator of renal disease, screen annually
  • Cortisol o Diurnal variation, higher in AM (5-23), decreased after 4pm (3-13) o Measures adrenal activity o Cushing – does not go down during day o Elevated – Cushing, ACTH producing tumor, hyperthyroid, obesity o Low – Addison disease, hypopituitary/thyroid, adrenal hyperplasia o Pregnancy, stress increases
  • ACTH (6- 58 F, 7 - 69 M) o Anterior pituitary function o Cushing – Low=pituitary cause/High=adrenal cause

o Osteoporosis: >2.5 SD below normal (<–2.5) o Done on postmenopausal women every 2 years o Annual for hyper parathyroid or long-term steroids

  • Calcium Levels (9-10.5 mg/dL, ionized 4.5-5.6) o Used to evaluate parathyroid function and calcium metabolism, to monitor patients with renal failure, renal transplantation, hyperparathyroidism, and various malignancies and to monitor calcium levels during and after large- volume blood transfusions. o When blood levels decrease, PTH is stimulated which stimulates release of calcium from reservoirs o Half is free and half is bound to albumin. Ionized measurements do not change d/t albumin o Symptoms of hypercalcemia may include anorexia, nausea, vomiting, somnolence, and coma. ▪ Most common cause is hyperparathyriod - HIV Testing o Viral load - accurate marker for prognosis, disease progression, response to antiviral treatment, and indication for antiretroviral prophylactic treatment. o Serology and virology: Standard for testing