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An exam covering topics related to the pentose phosphate pathway and various enzyme reactions involved in this metabolic process. The exam questions focus on identifying the specific enzymes responsible for different steps in the pathway, such as the enzymes that generate nadph, the enzymes involved in the two phases of the pathway, and the enzymes that catalyze the interconversion of various carbohydrate intermediates. The document also includes questions related to other biochemical concepts, such as the repair of oxidative damage by glutathione and the symptoms associated with wernicke-korsakoff syndrome. Overall, this exam seems to be designed to test the student's understanding of the pentose phosphate pathway, enzyme kinetics, and their application to various metabolic processes.
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Which enzyme in the pentose phosphate shunt creates both ribose-5-phosphate and xylulose-5- phosphate? - correct answer ✔✔Transketolase All of the molecules shown are used in the pentose phosphate pathway phase 2, which of them are substrates for trans aldolase? - correct answer ✔✔Fructose-6-phosphate, erythrose-4-phosphate, sedoheptulose-7-phosphate, and glyceraldehyde-3-phosphate Which enzyme in the pentose-phosphate shunt can generate NADPH? - correct answer ✔✔6- phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase In the pentose phosphate shunt phase 2, there are two enzymes. Which of the following is an enzyme from one of these reactions? - correct answer ✔✔Reaction 1: C5 + C5 <-> C7 + C3 (transketolase) Reaction 2: C3 + C7 <-> C6 + C4 (transaldolase) Reaction 3: C4 + C5 <-> C6 + C3 (transketolase) In the pentose phosphate shunt phase 1, there are two strong forward pulling reactions. Which of the following is an enzyme from one of these reactions? - correct answer ✔✔Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase You identify a protein with about 97% carbohydrate. This is best named as a - correct answer ✔✔Proteoglycan Phase 1 of PPP produces - correct answer ✔✔2 mol NADPH and CO Phase 2 of PPP produces - correct answer ✔✔G6P, fructose-6-phosphate, and glyceraldehyde-3- phosphate Oxidative damage can be repaired by glutathione. What is needed to restore glutathione? - correct answer ✔✔NADPH
A patient presents with memory loss and partial paralysis. There is a syndrome with these symptoms. Testing the binding ability of the failing enzyme would reveal what? - correct answer ✔✔The patient has S Wernicke-Korsakoff syndrome Dehydration of 2-phosphoglycerate produces? - correct answer ✔✔Phosphoenolpyruvate Isomerization of 2-phosphoglycerate produces? - correct answer ✔✔3-phosphoglycerate Oxaloacetate is transaminated to what acid? - correct answer ✔✔Aspartic acid or aspartate (D)