Pharmacology for January, Study notes of Pharmacology

Pharmacology for January Key points

Typology: Study notes

2020/2021

Uploaded on 06/03/2026

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nicole-pawlicke 🇺🇸

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THE LANGUAGE OF PHARMACOLOGY LEARNING OBJECTIVES
TERM
DEFINITION
drug
chemical that causes physiological effect
medicine
administered to elicit a therapeutic effect
toxicology
mechanisms by which chemicals produce
noxious effects on living tissues or organisms
pharmacodynamics
how drug affects a living system
pharmacokinetics
how living systems affects drug
pharmacogenetics
variations in drug response due to genetic
influence
pharmacogenomics
genetic factors to guide drug therapy
pharmacoepidemiology
variability of drug response across population
pharmacoeconomics
comparative cost-to-benefit ratios for
treatment strategies
pharmacovigilance
adverse effects of drugs
absorption
absorption from the site of administration
permits entry of the drug into plasm
distribution
drug may reversibly leave the bloodstream
and distribute into the interstitial and
intracellular fluids
metabolism
the drug may be biotransformed through
metabolism by the liver
elimination
the drug and its metabolites are eliminated
from the body in urine, bile, or feces
ROUTES OF ADMINISTRATION
ICV
intracerebroventricular
AS
left ear
AD
right ear
AU
both ears
pf3
pf4

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THE LANGUAGE OF PHARMACOLOGY LEARNING OBJECTIVES

TERM DEFINITION

drug chemical that causes physiological effect medicine administered to elicit a therapeutic effect toxicology mechanisms by which chemicals produce noxious effects on living tissues or organisms pharmacodynamics how drug affects a living system pharmacokinetics how living systems affects drug pharmacogenetics variations in drug response due to genetic influence pharmacogenomics genetic factors to guide drug therapy pharmacoepidemiology variability of drug response across population pharmacoeconomics comparative cost-to-benefit ratios for treatment strategies pharmacovigilance adverse effects of drugs absorption absorption from the site of administration permits entry of the drug into plasm distribution drug may reversibly leave the bloodstream and distribute into the interstitial and intracellular fluids metabolism the drug may be biotransformed through metabolism by the liver elimination the drug and its metabolites are eliminated from the body in urine, bile, or feces ROUTES OF ADMINISTRATION ICV intracerebroventricular AS left ear AD right ear AU both ears

SL sublingual OS left eye OD right eye OU both eyes PO orally by mouth IO intraosseous IT intrathecal NG nasogastric IP intraperitoneal IV intravenous TD transdermal ID intradermal SC subcutaneous IM intramuscular PR per rectally PV vaginally IU intrauterine IC intracardiac ● Enteral routes ○ Oral ■ Advantages ● Many different dosages ● Possible to reverse ● Different release rates ○ Immediate release ○ Enteric coated ○ Chewable/liquid ○ Extended release/delayed release ■ Disadvantages ● Complex ● First pass metabolism

● Nasal inhalation ○ Can be “topical” to sinus/nasal tissues ○ Can be systemic (naloxene, calcitonin) REVIEW QUIZ SLIDES ALSO!