Download SBB ASCP Practice Test | Actual Questions and Answers Latest Updated 2024/2025 (Graded A+ and more Exams Biology in PDF only on Docsity!
SBB ASCP Practice Test | Actual Questions and Answers Latest Updated
2024/2025 (Graded A+)
A donor experiences perioral paresthesia during an apheresis procedure. Which of the following should be performed? a. Increase the flow rate. b. Reduce the flow rate. c. Elevate the donor's feet. d. Have the donor breathe into a paper bag. - ✔✔b. Reduce the flow rate. A unit of autologous blood tested repeatedly reactive for HBsAg. The patient is scheduled for surgery in three days. What action should be taken? a. Discard the unit. b. Send the unit with a biohazard label and "autologous use only." c. Obtain a written request from the patient's physician and send the unit with a biohazard label and "autologous use only." d. Wait for confirmatory testing before contacting physician to see what he wants to do. - ✔✔c. Obtain a written request from the patient's physician and send the unit with a biohazard label and "autologous use only." Which of the following individuals can be accepted for allogeneic blood donation? a. Male, age 72, Hb 13.5, BP 124/8 8 b. Female, age 22, Hb 14.0, spontaneous abortion 5 weeks ago C. Female, age 37, Hb 12.2, BP 160/ d. Male, age 61, Hb 12, cardiac bypass surgery 4 years ago e. Female, age 61, Hb 13.5, breast cancer 5 years ago - ✔✔a. Male, age 72, Hb 13.5, BP 124/ A 64-year-old male prospective donor states that he had a positive TB skin test one year ago. When further questioned, he states that the x-ray was done and was negative with no other abnormal findings. You should: a. Accept the donor.
b. Defer the donor for 6 months. c. Defer the donor for 1 year. d. Defer the donor indefinitely. - ✔✔a. Accept the donor. A 27-year old truck driver has just finished donating blood and complained of tingling in his fingers and toes, and his fingers are in a strange rigid position. What should be done? a. Give the donor a beverage and cookies. b. Have the donor breathe into a paper bag. c. Ask the donor to lie down and elevate his feet. d. Administer oxygen immediately. - ✔✔b. Have the donor breathe into a paper bag. When preparing cryoprecipitate from plasma, the cryoprecipitate must be placed in the freezer within ___ after removal from the refrigerated centrifuge. a. 15 minutes b. 1 hour c. 6 hours d. 24 hours - ✔✔b. 1 hour FFP thawed but not used can be relabeled to: a. Liquid plasma b. Thawed plasma c. Recovered plasma d. Source plasma - ✔✔b. Thawed plasma Donated blood may NOT be used for allogeneic transfusion when HCV testing shows: a. EIA initial testing reactive b. EIA initial testing reactive and RNA testing nonreactive c. EIA initial testing reactive, and one of the duplicate repeat results is reactive
c. Autosomal dominant inheritance d. Non-paternity - ✔✔b. Autosomal recessive inheritance A disease is linked to the ABO system. The pedigree demonstrates: a. Parental haplotye b. Linkage disequilibrium c. Crossing over d. Nondisjunction - ✔✔c. Crossing over A trait carried on the Y chromosome will be passed from: a. Fathers to 50% of sons or daughters b. Fathers to 100% of sons and 50% of daughters c. Fathers to 100% of sons and no daughters d. Fathers to 100% of daughters and no sons - ✔✔c. Fathers to 100% of sons and no daughters A man who is genotype AO married a genotype OO woman. What is the probability that their first child will be type A? a. 12.5% b. 25% C. 50% d. 75% - ✔✔C. 50% Which of the following represent the biochemical structure of the H antigen on red cells? a. Cer-Glu-Gal-GlcNac-GalNac b. Cer-Glu-Gal-GlcNac-Gal-Fuc c. Cer-Glu-Gal-GlcNac-Glu-Fuc d. Cer-Glu-Gal-GlcNac-Gal-Glu - ✔✔b. Cer-Glu-Gal-GlcNac-Gal-Fuc
A man phenotypes A2, Le(a+b-). His saliva shows only Lea. Which of the following best represents his genotype? a. A2O, HH, Lele, Sese b. A2A2, Hh, lele, sese c. A2O, HH, Lele, sese d. A2O, Hh, lele, Sese - ✔✔c. A2O, HH, Lele, sese The following Rh phenotyping results are obtained. What is the most likely genotype? D=0, C=+, E=+, c=+, e=+, f= a. rr b. r'r c. r''r d. r'r" - ✔✔d. r'r" An Rh-negative woman has requested prediction of the Rh genotype of her offspring. Phenotyping results of her family shows the following results. What is the husband's most likely Rh genotype? Woman=dce, Her husband=DCce, Husband's mother= dCce, Husband's brother=Dce a. R1 r' b. r'r' c. R1 r d. R0r' - ✔✔d. R0r' The amino acid sequence responsible for the M antigen is: a. Leu-Ser-Thr-Thr-Glu b. Ser-Ser-Thr-Thr-Gly c. Leu-Ser-Ser-Thr-Glu d. Thr-Ser-Thr-Leu-Gly - ✔✔b. Ser-Ser-Thr-Thr-Gly The antigen that occurs in approximately 20% of individuals of African ethnicity is:
d. CH/RG:1,2,-3,11,12 - ✔✔b. CH/RG:1,2,3, 11, 12 Which antigen is located on the CR1 protein? a. Cra b. Kpc c. McCc d. Erc - ✔✔C. McCc The following family study illustrates which type of Lutheran Null inheritance? a. X-linked dominant inhibitor b. Autosomal dominant inhibitor, ln(Lu) c. Recessive gene at the Lutheran locus d. X-linked recessive - ✔✔b. Autosomal dominant inhibitor, ln(Lu) HLA-A 1 and HLA-88 are found more frequently than expected. This is known as:: a. Genetic drift b. Recombination c. Non-disjunction d. Linkage disequilibrium - ✔✔d. Linkage disequilibrium Refer to the HLA testing results below. A2, B12, C22, DR5 is best referred to as: Father A1,A9,B5,B8,Cw2,Cw7,DR3,DR Mother A2, A3, B7, B12 Cw2, Cw7, DR2 DRS Child 1 A1, A3 B7 B8,C w7,D R2,D R Child 2 A3, A9, B5, B7, Cw2, Cw7, DR2, DR Child 3 A1, A2, B8, 812, Cw2, Cw7, DR3, DR Child 4 A2,A9, B5,812,Cw2,DR5,DR Child 5 A2,A9,B5,812,Cw2,DR5,DR
Child 6 A2 , A9, B5, B12, Cw2, DR3, DR Child 7 A2, A11,8 12,817,C w2,C w3,D R1. DR a. Paternal phenotype b. Maternal locus c. Maternal haplotype d. Maternal allele - ✔✔c. Maternal haplotype Referring to the testing results of the question above, which child represents a recombinant? a. Child 2 b. Child 4 c. Child 5 d. Child 6 - ✔✔d. Child 6 - Cross-over paternal gene at Cw&DR You are investigating the relationship between an HLA antigen, A48, with a newly diagnosed skin disorder. Your have the following results. What is the relative risk that the person with HLA-A48 will also develop the skin disorder? HLA-A48 positive with skin disorder HLA-A48 neaative with skin disorder HLA-A48 positive without skin disorder HLA-A48 neaative without skin disorder a. 1. b. 2. C. 7. d. 16.6 - ✔✔d. 16.6 - ad/bc=(177)(220)/(34)(69)=16. What conclusion can be drawn from these testing results? Alleged father = A, MN, DCcEe Mother = O, N, dCce Child 1 = A2, N, DCce
The cell that regulates whether or not the immune response will occur is: a. B cells b. Dendritic cells c. Kupffer cells d. T cells - ✔✔d. T cells Class switching of activated B cells involves the conversion of: a. lgM to lgG b. lgG to lgM c. lgE to lgA d. lgA to lgG - ✔✔a. lgM to lgG T helper cells are: a. CD4+ b. CD8+ C. CD44+ d. CD55+ - ✔✔a. CD4+ CR1 receptors on macrophages recognize: a. C3b b. C3c c. C4c d. C4d - ✔✔a. C3b The lgG subclasses that are most efficient in activating complement are: a. lgG 1 , lgG b. lgG1, lgG c. lgG2, lgG
d. lgG2, lgG4 - ✔✔b. lgG1, lgG The Fc receptor on phagocytes that has the highest affinity for binding lgG is: a. FcR b. FCR2a c. FCR2b d. FCR e. FcR4 - ✔✔a. FcR The following QC testing results were obtained for ten apheresis platelets. According to the AABB Standards, the interpretation is: 3.15 X 10^ 5.56 X 10^ 2.89 X 10^ 3.74 X 10^ 3.15 X 10^ 5.51 X 10^ 4.89 X 10^ 4.24 X 10^ 5.89 X 10^ 3.88 X 10^ a. Unacceptable, 50% of the results are too low b. Unacceptable, 100% of the results are too low. c. Acceptable, 90% of the results meets standards d. Acceptable, 100% of the results meets standards - ✔✔c. Acceptable, 90% of the results meets standards Hospital blood banks that collect blood but do not ship across state lines must be: a. Licensed by the FDA
a. 6 months b. 1.5 years c. 5 years d. Never - ✔✔b. 1.5 years An employee who has been employed for the last 4 years failed a proficiency survey. This employee has received favorable performance appraisal and passed the two previous proficiency surveys, as well as achieving 100% on all competency assessments. As the supervisor, you should: a. Document the non-compliance with the QA department. b. Counsel the employee and then document the counseling with the QA department. c. Determine the cause of error, retrain or counsel depending on the cause and document. d. Suspend the employee until proper retraining can be conducted. - ✔✔c. Determine the cause of error, retrain or counsel depending on the cause and document. Autologous blood is to be collected from a 75-lb individual into a 500-ml blood collection bag. Approximately How much whole blood should be collected? a. 333 b. 357 C. 404 d. 449 - ✔✔b. 357 (75/2.2= 34kgx10.5mL/kg= 357) You have 22 random units of Red Blood Cells on the shelf. For which of the following patients could you find 3 compatible units? a. 0 positive with anti-f b. A positive with anti-Jka c. B negative with anti-D d. 0 positive with anti-Fya - ✔✔d. 0 positive with anti-Fya (.45x.85x.34= 3/X; X=23 units)
If a dose of RhlG is given at 28 weeks resulted in a circulating anti-D titer of 16, about how many more weeks will it take for the titer to reach 4? a. 2 b. 4 C. 7 d. 12 - ✔✔C. 7 (16=0; 8=23; 4=46; days= 6.7 weeks) The gene frequency of a new antigen BBa is 0.8. How many individuals would be expected to be BBa BBb? a. 32% b. 40% c. 64% d. 80% - ✔✔a. 32% [2(.8)(.2)= 32] Given the following information, determine the number of FTEs required for the workload. Vacation/year = 2 weeks Average sick days/year = 5 days Holidays/year = 6 days Continuing education = 4 days Productivity = 75% (45 min/hr) Annual workload = 400,000 units a. 3 b. 5 C. 7 d. 9 - ✔✔b. 5 (400,000/84,600= 4.7)
a. Hb C trait b. Hb C disease c. Hb SC disease d. Hb SS disease - ✔✔b. Hb C disease A 58-year-old female was admitted for an elective hysterectomy. Upon admission, the patient is noted to have enlarged lymph nodes. She states that she has felt tired for the past several weeks. Her pre-op lab results are as follows. What is the likely diagnosis? Hb 8.8 q/dl, HCT 23.5%, WBC 55,000/mm3, PLT 95,000/mm3, Diff 23 segs, 48 lymphs, 15 monos, 14 smudge cells a. ALL b. CLL c. AML d. CML - ✔✔b. CLL (history & CBC (lymphs) fits CLL 90% of the ATP needed by red blood cells is generated in: a. Methemoglobin reductase pathway b. Hexose monophosphate shunt c. Embden-Meyerhoff pathway d. Leubering-Rapoport shunt - ✔✔c. Embden-Meyerhoff pathway Prothrombin complex is indicated for the treatment of: a. Mild von Willebrand's disease b. Severe hemophilia A without Factor VIII inhibitors c. Severe hemophilia A with Factor VIII inhibitors d. Severe Christmas disease - ✔✔d. Severe Christmas disease In a presurgical work-up, a patient's platelet count was normal and the PT, PTT, and TT were slightly prolonged. Inspection of the clot from the PT and PTT shows poor clot formation. Which factor is most likely deficient?
a. Factor X b. Factor XIII c. Fibrinogen d. Prothrombin - ✔✔b. Factor XIII A patient is admitted to the emergency department following a minor auto accident. Routine screening tests show the following results. No other patient history is available. What is the factor deficiency? Platelet count 2000,000/mm 3, PT 19.2 sec (control 14.8 sec), PTT 28.4 sec ( control 27.6 sec) a. V b. VII c. X d. XIII - ✔✔b. VII A 5-year-old boy presented with a bruised arms and legs. His mother stated that the bruising typically appeared without injury. Past medical history revealed that at 3 years of age the patient had an episode of nosebleed that required transfusion of one unit of blood. There was a family history of bleeding on the maternal side of the family. The patient's mother and maternal grandmother had abnormal bleeding. Physical examination revealed multiple bruises over the extremities. Laboratory testing shows the following results. PT 12.5 sec, PTT 39 sec, Platelets 255,000/uL Factor VIII level 60%, vWF:Aa 40% Which of the following is a treatment option? a. DDAVP b. Factor VIIa c. Factor IX concentrate d. Fresh Frozen Plasma - ✔✔a. DDAVP A 20-year-old male is admitted in the emergency department for a swollen knee after a falling accident. What is the diagnosis? PT 13 sec, PTT 65sec, Plt 45,000/uL, PTT 1:1 mix 33 sec at 0 min & 34 at 90 min a. van Willebrand disease b. Hemophilia A c. Fibrinogen deficiency
a. Blocked Rh antigen b. ABO incompatibility c. Rh incompatibility d. Antibody to a low-prevalence antigen - ✔✔d. Antibody to a low-prevalence antigen Refer to the same question above. Which of the following procedures would best resolve the discrepancy? a. Elute the antibody and perform a routine panel. b. Elute the antibody and test with A, B, and O cells. c. Elute the antibody and test with the father's red cells. d. Test the maternal serum with the baby's red cells. - ✔✔c. Elute the antibody and test with the father's red cells. Prenatal testing results indicate a woman was Rh negative. After delivery, a microscopic mixed-field agglutination is noted on the weak D test. You should: a. Report the patient is Rh positive. b. Give the patient one vial of RhlG. c. Do a Kleihauer-Betke stain. d. Do a DAT on the patient's cells. - ✔✔c. Do a Kleihauer-Betke stain. A KB test shows 18 fetal cells in 2000 adult cells. What is the volume of the fetal-maternal hemorrhage? a. 30 ml b. 40 ml c. 45 ml d. 55 ml - ✔✔c. 45 ml (18/2000)(5000)= 45 ml
A woman who delivered a normal term infant shows the following lab testing results. These results indicate: Mother: O Neg, Anti-D identified, titer= Infant: A Pos, DAT Neg a. The mother is a candidate for RhlG. b. The mother is NOT a candidate for RhlG. c. Further investigation is needed to decide RhlG candidacy. d. There are fetal cells in her circulation - ✔✔c. Further investigation is needed to decide RhlG candidacy (Could be anti-D Antepartum RhIG) Neonatal alloimmune thrombocytopenia is caused primarily by which antibody? a. Anti-HLA Class I b. Anti-HPA-1 a c. Anti-HPA-1 b d. Anti-HNA-1 a e. Anti-HNA-1 b - ✔✔b. Anti-HPA-1 a Polymerase chain reaction: a. Involves the use of restriction enzymes that cut DNA into segments. b. Detects gene duplication and deletions. c. Uses DNA polymerase to replicate and amplify a specific gene sequence. d. Use probes such as cDNA or oligonucleotides to find a specific part of the gene. - ✔✔c. Uses DNA polymerase to replicate and amplify a specific gene sequence The development of protein from RNA is referred to: a. Transcription b. Translation c. Recombination d. Activation - ✔✔b. Translation
