Semi-solids Dosage Forms Development, Lecture notes of Pharmaceutical Chemistry

Semi-solids Dosage Forms Development

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2020/2021

Uploaded on 02/10/2022

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Semi-solids Dosage Forms Development
Semi-solids constitute a large proportion of the drug formulation. They are used as
carriers for drugs that are topically delivered by way of the skin, rectal tissue, vagina,
cornea, urethral membrane, nasal mucosa, and so on. Semi-solids dosage forms are
advantageous for a wide variety of drug molecules in terms of their ease of use, rapid
preparation and local delivery capabilities. There are a variety of dosage forms for
semi-solid, each with unique characteristics, they can be applied on the affected area
directly and the administration of this dosage form to be readily administered to
patients of any age. Semi-solids dosage forms usually presented in the form of
ointments, gels, creams and suppositories, and these dosage forms consist of one or
more active ingredients that dissolved or uniformly dispersed in a suitable base and
any suitable excipients.
Fig.1 The basic bases of various semisolid dosage forms (ointments, creams, and
gels).
The team of CD Formulation is leading experts in all aspects of pharmaceutical
formulation development and dosage form optimization, we can accord the
characteristics of the API and the development goals of the customers to design the
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Semi-solids Dosage Forms Development

Semi-solids constitute a large proportion of the drug formulation. They are used as carriers for drugs that are topically delivered by way of the skin, rectal tissue, vagina, cornea, urethral membrane, nasal mucosa, and so on. Semi-solids dosage forms are advantageous for a wide variety of drug molecules in terms of their ease of use, rapid preparation and local delivery capabilities. There are a variety of dosage forms for semi-solid, each with unique characteristics, they can be applied on the affected area directly and the administration of this dosage form to be readily administered to patients of any age. Semi-solids dosage forms usually presented in the form of ointments, gels, creams and suppositories, and these dosage forms consist of one or more active ingredients that dissolved or uniformly dispersed in a suitable base and any suitable excipients.

Fig.1 The basic bases of various semisolid dosage forms (ointments, creams, and gels).

The team of CD Formulation is leading experts in all aspects of pharmaceutical formulation development and dosage form optimization, we can accord the characteristics of the API and the development goals of the customers to design the

formulation of ointments. CD Formulation can provide you with one-stop services to meet your needs of ointments.

We Can Provide You with The Following Services

Ointments

Creams

Suppositories

The Advantages of Semi-solids Dosage Forms

 External use

 Reduce the possibility of side effects

 Avoid first-pass intestinal and liver metabolism.

 Patient compliance is increased

Five Unit Operation for Semi-solids Dosage Forms

 Mixing of liquids

 Mixing and blending of solid

 Mixing and blending of semisolid

 Dispersing

 Milling and size reduction of solid and semisolid