Target 3D Structure Analysis: Obtaining Accurate Information for Drug Discovery, Slides of Biology

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Target Structure Analysis

Target 3D Structure Analysis

Target structure information can be utilized in multiple links of drug discovery, such as target selection,

identification and optimization of hits, development of final properties of compounds using multi-

threaded processes, as well as reconstruction of biological macromolecular structures by rational design

to optimize their drugability. Moreover, the high drug attrition rate associated with late-phase clinical

trials in drug development is an important reason for the rising cost, which further promotes the

demand for obtaining accurate target three-dimensional (3D) structure information to reduce the

possibility of drug failure. Leveraging extensive expertise in structural biology and in silico drug

design, Creative Biostructure provides comprehensive target 3D structure analysis solutions.

How Can We Help You Obtain the Target 3D Structure Information?

Structure determination is the process of obtaining the 3D position coordinates of the target molecule

by appropriate approaches. Creative Biostructure supports a variety of experimental techniques to

determine the structure, such as X-ray crystallography, cryo-electron microscopy, NMR spectroscopy, etc.

Our one-stop gene-to-protein and gene-to-structure services have solved many problems in the field of

membrane proteins and structural biology for customers from global academia and the pharmaceutical

industry.

Thank you!

Excerpt from:

https://drug-discovery.creative-biostructure.com/target-

3d-structure-analysis-p