Entrega 1 (fecha entrega 15/10/12)
GENÉTICA MOLECULAR
1- Si el peso molecular medio de un nucleótido es de 350,
a) ¿Cual será la longitud total del DNA en una célula diploide humana que contiene
6.l0-12g de DNA?
b) ¿Qué implica este resultado respecte a la configuración intranuclear del DNA?
2- En la tabla siguiente se indican las proporciones en bases de ácidos nucleicos
correspondientes a ocho especies diferentes. Determinar si el ácido nucleico es ADN o
ARN, y si es de cadena doble o sencilla. Razona las respuestas.
Espècie T C U A G
1 31 19 31 19
2 19 31 31 19
3 19 31 19 31
4 1 1,26
5 32 18 25 25
6 25 32 23 20
7 1,26 1
8 1 1
3- Imagine it’s the year 2015. Because the Martian landers discovered that liquid water
was present on Mars, another probe was sent to look for signs of life. Cells containing
double-stranded DNA were found, and using an automated variant of the Meselson-
Stahl experiment, had the original DNA labeled with 14N and then transferred to 15N
(note that this is the reverse of the original M-S experiment). In the low temperatures of
Mars, the replication machinery works slower, so each cell division takes 60 hours.
Assume you do not know if replication machinery uses a dispersive, conservative, or
semiconservative approach. Predict what the centrifuge tube patterns should be at 60,
120, 180, and 240 hours.
