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BACTERIAL CELL STRUCTURE & FUNCTION BACTERIAL CELL STRUCTURE & FUNCTION
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what are the 5 major groups of microorganisms? - ANSWER-1) bacteria (prokaryote)
what is the process by which bacterial replication occurs? - ANSWER-binary fision T/F: bacterial DNA is double stranded, circular, and within in a nucleoid in the cytoplasm
bacterial energy production: anaerobic - ANSWER-uses glycolysis and fermentation
homologous recombination - ANSWER-Exchange of genetic information between homologous DNA molecules. site specific recombination - ANSWER-requires very little sequence homology between the recombining DNA molecules (unique sequence) Transposition (transposons) - ANSWER-Segment of DNA can jump (excision and reincorporation) from one location to another, can transfer genes from plasmid to choromosome and vice versa. classification of bacteria - ANSWER-- Genus species
cephlalosporin abx mechanism of action - ANSWER-binds to PBPs and prevent them from cross-linking peptidoglycan, leading to disruption of cell wall synthesis and bacterial death. cephalosporin (3rd generation) modifications to enhance activity - ANSWER-1) hydrophilic -> able to navigate through porins
metronidazole mechanism of action - ANSWER-reduced by pyruvate-ferredoxin oxidoreductase leading to a reactive radical that will interact with DNA leading to strand destabilization and breakage