X-ray Crystallography Data Analysis and Processing Service by Creative Biostructure, Slides of Biology

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Crystallography Data

Analysis service

Creative Biostructure can provide a pipeline of X-ray crystallography

data analysis and processing service based on our comprehensive

X-ray Crystallography Platform. Our mission is to provide state-of-the-

art data analysis service to researchers from both industrial and

academic organizations, enabling precise three-dimensional (3D)

structure analysis of biological macromolecules that play essential roles

in human health.

After obtaining the initial phases, an electron density map can be

computed, and the process of model building and refinement will begin.

Model building and refinement are conducted in iterative cycles till the

R-factor converges to an appropriate low value with an appreciable

geometry of the atomic model. By this, we will provide a high-quality

model that nicely fits the electron density map. The quality of the final

model will be validated by programs like PROCHECK. Upon request, we

can also help deposit the final structure into Protein Data Bank (PDB),

conduct detailed structural analysis, and provide high-quality figures for

publication.

• Creative Biostructure offers a range of analytical services including:
• Phase determination
• X-ray diffractometry pattern indexing
• Single peak fitting
• Database mining
• Single-crystal structure solution
• Single-crystal refinement
• Structural refinement (Model building and phase refinement)
• Quantitative analysis
• Microtextural analysis
• Amorphous phase quantitative analysis
• Parametric refinement
• Integration (the measurement of the diffracted intensities)
• Structure solution from powder data

Creative Biostructure provides experimental and computational

facilities for X-ray based structure analysis and refinement. Our

professional crystallographers are highly experienced and motivated to

provide exceptional quality services. Our team has years of experience

in handling complex crystallography research projects and strives for

excellent data and interpretation.

Excerpt from:

https://www.creative-biostructure.com/crystallography-data-

analysis.htm