Genetics Exam 1 Practice tests updated revised version, Exams of Nursing

Genetics Exam 1 Practice tests updated revised version

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Genetics Exam 1 Practice tests updated revised
version
1.
For the following two questions, consider the following double-
stranded DNA sequence:
5'-ATCATGCCATG-3'
3'-TAGTACGGTAC-5'
1)How many hydrogen bonds are represented in this double helix?
A) 16 B) 9 C) 20 D) 27 E) 8: D
2.
5'-ATCATGCCATG-3'
3'-TAGTACGGTAC-5'
2)How many phosphodiester bonds are represented in this double
helix?
A) 9 B) 23 C) 8 D) 20 E) 16: D
3. aa Bb Cc DD Ee FF
3)How many different gametes can this individual produce?
A) 10 B) 6 C) 12 D) 8 E) 24: D
4. 4) Suppose only one of the gametes is randomly selected. What is
the proba-
bility that the gamete
with the following combination of alleles is selected?
abCDeF
A) 1/12 B) 1/24 C) 1/8 D) 1/4 E) 1/6: C
5.
5) InDrosophila virilis, nuclei of somatic cells contain 12
chromosomes while nuclei of sperm cells
contain only 6 chromosomes. What does "n" equal for this species?
A) 12
B) 24
C)3
D)
6 or 12, depending on cell type
pf3
pf4
pf5
pf8
pf9
pfa
pfd
pfe
pff

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Genetics Exam 1 Practice tests updated revised

version

  1. For the following two questions, consider the following double- stranded DNA sequence: 5'-ATCATGCCATG-3' 3'-TAGTACGGTAC-5'
  1. How many hydrogen bonds are represented in this double helix? A) 16 B) 9 C) 20 D) 27 E) 8: D
  1. 5'-ATCATGCCATG-3' 3'-TAGTACGGTAC-5'
  1. How many phosphodiester bonds are represented in this double helix? A) 9 B) 23 C) 8 D) 20 E) 16: D
  1. aa Bb Cc DD Ee FF
  1. How many different gametes can this individual produce? A) 10 B) 6 C) 12 D) 8 E) 24: D
    1. Suppose only one of the gametes is randomly selected. What is the proba- bility that the gamete with the following combination of alleles is selected? abCDeF A) 1/12 B) 1/24 C) 1/8 D) 1/4 E) 1/6: C
    1. InDrosophila virilis, nuclei of somatic cells contain 12 chromosomes while nuclei of sperm cells contain only 6 chromosomes. What does "n" equal for this species? A) 12 B) 24 C) 3 D) 6 or 12, depending on cell type

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E)6: E

    1. Which evolutionary process relies on the premises that individuals with the best adaptations are most successful at reproducing and leave more offspring than those with less adaptive forms and that those adaptations have genetic basis? A) migration B) natural selection C) mutation D) population genetics E)random genetic drift: B
    1. Consider a cross between two individuals with the following genotypes at three traits that assort independently: Rr Ss TT x rr Ss Tt What is the probability that an offspring will be R/r; s/s; T/T? A) 5/8 B) 1/16 C) 1/4 D) 1/8 E) 3/8: B
    1. Consider the cross of the previous question , and assume all capital alleles are dominant. What is the probability of having an offspring that shows all the dominant traits? A) 3/4 B) 3/8 C) 1/4 D) 1/8 E) 3/16: B
    1. Mutations at theRb gene lead to dominant cancer that has incomplete penetrance. How is the penetrance explained? A) Cancer will develop in Rb+Rb- individuals when cells become homozygoues for the Rballele after rare mitotic recombination events. B) Penetrance is due to the interaction with the environment. C) Rb-Rb- is lethal D) Incomplete penetrance is due to interactions with other genes. E)There is codominance.: A
    1. Crossingover involves the breakage and reunion of

4 / 17 A) 450 brown: 150 green B) None of the answers is correct C) 300 brown: 300 green D) 350 brown: 250 green E) 500 brown: 100 green:

    1. Suppose you wanted to test using a chi-square test, if the observations fit the expectations. How many degrees of freedom would this test have? A) 1 B) 5 C) 2 D) 4 E) 3A: A
    1. Suppose a somatic cell at G1 has 5 pg of DNA in a newly discovered species. How much DNA will a gamete have? A) 5 pg B) 20 pg C) 2.5 pg D) 15 pg E) 10 pg: C
    1. In a plant in wich 2n=24, what is the total number of chromatids present during prophase I of meiosis? A) There is not enough information to answer this question B) 48 C) 96 D) 12 E)24: B
    1. When a diploid cell divides by mitosis, the result is A) four unique haploid cells. B) two identical diploid cells. C) two identical haploid cells. D) four identical haploid cells. E)four unique diploid cells.: B
    1. Which of the following individuals was instrumental in understanding genetic linkage? A) Thomas Hunt Morgan B) Rosalind Franklin C) Gregor Mendel

5 / 17 D) James Watson E)Francis Crick: A

    1. Normal parents have a Tay-Sachs child. Tay-Sachs is a recessive condition. What is the probability that their next child will be normal? A) 0 B) 0.75 C) 0.5 D) 0.25 E) 1: B
    1. A double-stranded DNA molecule has 22% adenine. What proportion of cytosine does this molecule have? A) 28% B) 12% C) 100% D) 38% E) 72%: A
    1. The complementary sequence of 5' AATTCGCTTA 3' is... A) 5' TAACGCTTAA 3' B) 5' AATTCGCTTA 3' C) 5' TAAGCGAATT 3' D) 3' TAAGCGAATT 5' E)3' AATTCGCTTA 5': C
    1. You identified a biochemical pathway that produces pigment in a flower. The pathway involves converting a precursor compound into the pignment. Two genes work one after the other to carry out the reactions using the precursors produced by the other gene. When you perform a dihybrid cross, what is the phenotypic ratio (purple:white) you expect to see? A) 9:7 B) 15:1 C) 9:3:3:1 D) 12:3:1 E) 9:6:1: A
    1. Using the information provided in the previous question, what would we say about how the two genes determine the phenotype? A) there is incomplete dominance B) the genes act independently C) there is not enough information to answer the question

7 / 17 the domi- nance relationships between these allleles is A1=A2? A) 3 and 3 B) None of the answers is correct C) 1 and 1 D) 2 and 2 E) 3 and 2: A

    1. Two proteins interact to form a multimeric complex. When one of the proteins is mutated, there is a substantial loss of functional activity in the multimeric protein. This type of mutation is classified as A) hypermorphic. B) amorphic. C) hypomorphic. D) neomorphic. E)dominant negative.: E
    1. Which mode of inheritance results in the phenotype of a heterozygote being indistinguishable from that of an organism homozygous for the dominant allele? A) epistasis B) incomplete dominance C) codominance D) complete dominance E)incomplete penetrance: D
    1. The separation of sister chromatids during anaphase I of mitosis is known as chromosome A) synapsis. B) crossing over. C) cytokinesis. D) disjunction. E)karyokinesis.: D

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  1. >1) It is now history that Francis Crick said "We have discovered the secret of life" after having worked out the structure of the double helix of DNA together with James Watson. Why did he say this? A) the structure revealed how DNA and proteins could work together during cell division B) the structure revealed how the DNA carried information that can be copied, can mutate and can evolve, i.e., essential features for life C) the structure revealed that DNA was the hereditary material D) the DNA is a nucleic acid like RNA E)B and D are correct: B
  2. >2) What is the best explanation for Chargaff's rules? A)there is always double amount of pyrimidine than purine bases in the double helix of DNA B) there is pairing between G and T and A and C in the double helix of DNA C) there is pairing between G and C and A and T in the double helix of DNA D) there is pairing between G and C and A and U in the RNA E)C and D are correct: C
  3. >3) Most people with the dominant mutant polydactyly allele have extra digits, but at least 25% have the normal number of digits. What is the genetic explanation for this observation? A) incomplete penetrance B) temperature-sensitive allele C) lethal allele D) dominant negative allele E)partial dominance: A
  4. >4) A DNA double helix molecule that is 100 base pairs long

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  1. >8) Which protein complex is responsible for holding together homologous chromosomes during metaphase I of meiosis? A) separase B) cohesin C) synaptonemal complex D) DNA polymerase E)microtubules: C
  2. >9) If a typical somatic cell has 64 chromosomes, how many chromosomes are expected in each gamete of that organism? A) 8 B) 16 C) 32 D) 64 E)128: C
  3. >10) Which of the following are correct equations with regard to the percent- age of nucleotides in single-stranded RNA? A) (G+A)/(C+U) = 1 B) G/C = 1 C) A/U = 1 D) Answers A, B, and C are all correct E)Without the actual sequence, you can not determine these ratios: E
  4. >16) Cells control the progression of the cell cycle by monitoring certain checkpoints. The progression through these checkpoints depends on: A) the expression of mutated tumor-suppressor genes B) the accumulation of microtubules C) the synthesis of DNA during G D) the direct contact between cyclins and DNA

11 / 17 E)the interactions of specific cyclins and cyclin-dependent kinases: E

  1. >17) For the purposes of this question, assume that a G somatic cell nucleus in a female Myrmecia pilosula contains 2 picograms of DNA. How much DNA would be expected in a metaphase I cell of a female? A) 32 picograms B) 8 picograms C) 16 picograms D) 4 picograms E)Not enough information is provided to answer the question.: D
  2. >18) Most combinations of different ABO alleles result in complete domi- nance of one allele. Which combination results in codominance? A) ii B) IBi C) IAi D) IAIB E)either IAi or IBi: D
  3. >20) Which of the following individuals proposed the chromosomal theory of inheritance? A) Thomas Hunt Morgan B) James Watson C) Francis Crick D) Rosalind Franklin E)George Beadle and Edward Tatum: A
  4. >22) You perform a cross between a trihybrid for three recessive traits with a tester. How many phenotypic classes would you have? What ratio of the offspring do you expect of each? A) 8 and 27:9:9:9:3:3:3: B) 4 and 9:3:3:

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E)26: D

  1. >26) During interphase of the cell cycle,. A) the nuclear membrane disappears B) sister chromatids move to opposite poles C) DNA content essentially doubles D) RNA replicates E)DNA recombines: C
  2. >27) Which of the following is true regarding Gregor Mendel? A) He used peas in his experiments. B) His work only became prominent when they were re-discovered decades after he published his work. C) He concluded that discrete "factors" were important for the inheritance of traits. D)While he was a contemporary of Charles Darwin (they lived at the same time), his work was unknown to Darwin. E)All of the above are true regarding Gregor Mendel.: E
  3. >30) Which of the following is NOT correct with regard to percentage of nucleotides in doublestranded DNA? A) A/T = 1 B) G/C = 1 C) (G+A)/(C+T) = 1 D) (G+T)/(C+A) = 1 E)(G+C)/(T+A) = 1: E
  4. >31) You identified a biochemical pathway that produces pigment in a flower. It involves two intermediates and two enzymes, R and T, to complete the pathway, as shown below. Dominant

14 / 17 alleles at R and T (R and T , respectively), are wild-type and perform the necessary reactions to complete the pathway. Recessive alleles (r and t ) are unable to complete their function. You perform a dihybrid cross (RrTt x RrTt ). Assuming the genes are on different chromosomes, what is the phenotypic ratio (pigmented:non-pigmented flowers) that you expect to see in the offspring? Precurser 1 > R > Precurser 2 > T> Pigment A) 9:3:3: B) 3: C) 1:2: D) 9: E)15:1: D

    1. An allele of a particular gene in a population of bacteria had a frequency of 0.36. Over time, the frequency of that allele became 0.47. Which of the following could have caused the change in allele frequency? A) natural selection B) genetic drift C) gene flow D) mutation E)ALL of the above could influence the change in allele frequency: E
    1. An individual has a genotype of Aa Bb dd jj Yy at five independently assorting genes. How many different gametes can this individual produce with respect to these genes? A) 4 B) 8 C) 16

16 / 17 population, if there are 3 different alleles for a gene (A1, A2 and A3)? How many different phenotypes can you have if the dominance relationships of this series are A1>A2>A3? A) 3 and 3 B) 6 and 5 C) 27 and 8 D) 6 and 3 E)none of the above answers is correct: D

    1. Hemophilia is an X-linked recessive trait. In a family, the mother knows she is a carrier and the father does not have the disease. The family is expecting triplets. They are worried about having boys that would have 50% chance of being affected. What is the probability of having one or more than one boy? Consider two scenarios: if the triplets are monozygotic and if the triples are trizygotic. A) 1/2 and 7/ B) 1/2 and 1/ C) 2/3 and 1 D) 1/3 and 1/ E)none of the above answers is correct: A
    1. A pea plant heterozygous for plant height, pod shape and flower color was selfed. The progeny consisted of 272 tall, inflated pods, orange flowers; 92 tall, inflated, white flowers; 88 tall, flat pods, orange; 93 dwarf, inflated, orange; 35 tall, flat, white; 31 dwarf, inflated, white; 29 dwarf, flat, orange; 11 dwarf, flat, white. For all of these traits there is a dominant allele and a recessive allele. You would like to perform a Chi-square test to see if the observations

17 / 17 fit the expectations of Mendel's laws. How many degrees of freedom will this test have? A) 2 B) 1 C) 7 D) 8 E)there is not enough information in the question to know the degrees of freedom for the test: C