Download Safety Data Sheet for Benzocaine: Identification, Hazards, and Safety Measures and more Exams Printing in PDF only on Docsity!
Safety Data Sheet
acc. to OSHA HCS
Printing date 05/06/2021 Revision date 05/06/
1 Identification
ยท (^) Product identifier
ยท (^) Trade name: Benzocaine ยท Synonym Ethyl 4-Aminobenzoate H-4-Abz-OEt NSC 4688 NSC 41531 4-amino-benzoic acid, ethyl ester
ยท Article number: (^) 20132 ยท CAS Number: 94-09- ยท EC number: 202-303- ยท Application of the substance / the mixture This product is for research use - Not for human or veterinary diagnostic or therapeutic use. It is the responsibility of the purchaser to determine suitability for other applications.
ยท Details of the supplier of the safety data sheet ยท (^) Manufacturer/Supplier: Cayman Chemical Co. 1180 E. Ellsworth Rd. Ann Arbor, MI 48108 USA
ยท Information department: Product safety department ยท Emergency telephone number: During normal opening times: +1 (734) 971- US/CANADA: 800-424- Outside US/CANADA: 703-741-
2 Hazard(s) identification
ยท Classification of the substance or mixture
d~
GHS08 Health hazard
STOT SE 1 H370 Causes damage to organs.
d~
GHS
Skin Sens. 1 H317 May cause an allergic skin reaction. ยท (^) Label elements ยท GHS label elements The substance is classified and labeled according to the Globally Harmonized System (GHS). (Contd. on page 2) US
Safety Data Sheet
acc. to OSHA HCS
Printing date 05/06/2021 Revision date 05/06/
Trade name: Benzocaine
(Contd. from page 1) ยท Hazard pictograms
d~
GHS
d~
GHS
ยท (^) Signal word Danger ยท Hazard statements H317 May cause an allergic skin reaction. H370 Causes damage to organs. ยท Precautionary statements P260 Do not breathe dust/fume/gas/mist/vapors/spray. P264 Wash thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P272 Contaminated work clothing must not be allowed out of the workplace. P280 Wear protective gloves. P302+P352 If on skin: Wash with plenty of water. P307+P311 IF exposed: Call a POISON CENTER or doctor/physician. P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P321 Specific treatment (see on this label). P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. ยท Classification system: ยท (^) NFPA ratings (scale 0 - 4)
0
0 0
Health = 0 Fire = 0 Reactivity = 0
ยท (^) HMIS-ratings (scale 0 - 4)
HEALTH FIRE REACTIVITY
0 0
Health = * Fire = 0 Reactivity = 0
ยท Other hazards ยท (^) Results of PBT and vPvB assessment ยท PBT: Not applicable. ยท (^) vPvB: Not applicable.
3 Composition/information on ingredients
ยท Chemical characterization: Substances ยท CAS No. Description 94-09-7 Benzocaine ยท (^) Identification number(s) ยท EC number: 202-303- US (Contd. on page 3)
Safety Data Sheet
acc. to OSHA HCS
Printing date 05/06/2021 Revision date 05/06/
Trade name: Benzocaine
(Contd. from page 3) ยท Information about protection against explosions and fires: No special measures required.
ยท Conditions for safe storage, including any incompatibilities ยท (^) Storage: ยท Requirements to be met by storerooms and receptacles: No special requirements. ยท (^) Information about storage in one common storage facility: Not required. ยท Further information about storage conditions: None. ยท (^) Specific end use(s) No further relevant information available.
8 Exposure controls/personal protection
ยท Additional information about design of technical systems: (^) No further data; see item 7.
ยท Control parameters ยท Components with limit values that require monitoring at the workplace: Not required. ยท (^) Additional information: The lists that were valid during the creation were used as basis.
ยท (^) Exposure controls ยท Personal protective equipment: ยท (^) General protective and hygienic measures: Keep away from foodstuffs, beverages and feed. Immediately remove all soiled and contaminated clothing. Wash hands before breaks and at the end of work. ยท Breathing equipment: Not required. ยท (^) Protection of hands:
_S
Protective gloves
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation ยท Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. ยท (^) Penetration time of glove material The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed. ยท Eye protection: (^) Not required.
9 Physical and chemical properties
ยท Information on basic physical and chemical properties ยท (^) General Information ยท Appearance: Form: Crystalline Color: Not determined. ยท (^) Odor: Characteristic ยท Structural Formula C9H11NO ยท Molecular Weight 165.2 g/mol (Contd. on page 5) US
Safety Data Sheet
acc. to OSHA HCS
Printing date 05/06/2021 Revision date 05/06/
Trade name: Benzocaine
(Contd. from page 4) ยท (^) Odor threshold: Not determined.
ยท (^) pH-value: Not applicable.
ยท (^) Change in condition Melting point/Melting range: 88โ90 ยฐC (190.4โ194 ยฐF) Boiling point/Boiling range: 172 ยฐC (341.6 ยฐF) ยท (^) Flash point: Not applicable.
ยท (^) Flammability (solid, gaseous): Product is not flammable.
ยท (^) Decomposition temperature: Not determined.
ยท (^) Auto igniting: Not determined.
ยท (^) Danger of explosion: Product does not present an explosion hazard.
ยท Explosion limits: Lower: (^) Not determined. Upper: Not determined.
ยท Vapor pressure: Not applicable.
ยท Density: Not determined.
ยท Bulk density: 320 kg/mยณ ยท (^) Relative density Not determined. ยท Vapor density Not applicable. ยท (^) Evaporation rate Not applicable.
ยท (^) Solubility in / Miscibility with Water at 25 ยฐC (77 ยฐF): 0.4 g/l
ยท Partition coefficient (n-octanol/water): Not determined.
ยท Viscosity: Dynamic: Not applicable. Kinematic: Not applicable. SOLUBILITY ~0.16 mg/ml in a 1:5 solution of EtOH:PBS (pH 7.2); ~30 mg/ ml in EtOH & DMSO; ~25 mg/ml in DMF
ยท Other information No further relevant information available.
10 Stability and reactivity
ยท Reactivity No further relevant information available. ยท (^) Chemical stability ยท Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications. ยท (^) Possibility of hazardous reactions No dangerous reactions known. ยท Conditions to avoid No further relevant information available. ยท (^) Incompatible materials: strong oxidizing agents ยท Hazardous decomposition products: carbon oxides, nitrogen oxides
11 Toxicological information
ยท RTECS Number DG (Contd. on page 6) US
Safety Data Sheet
acc. to OSHA HCS
Printing date 05/06/2021 Revision date 05/06/
Trade name: Benzocaine
(Contd. from page 6) ยท (^) UN proper shipping name ยท DOT, IMDG, IATA not regulated
ยท Transport hazard class(es)
ยท DOT, ADN, IMDG, IATA ยท (^) Class not regulated
ยท (^) Packing group ยท DOT, IMDG, IATA not regulated
ยท Environmental hazards: Not applicable.
ยท Special precautions for user Not applicable.
ยท Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code Not applicable.
ยท UN "Model Regulation": not regulated
15 Regulatory information
ยท Safety, health and environmental regulations/legislation specific for the substance or mixture No further relevant information available. ยท (^) Sara ยท Section 355 (extremely hazardous substances): Substance is not listed. ยท (^) Section 313 (Specific toxic chemical listings): Substance is not listed. ยท TSCA (Toxic Substances Control Act): ACTIVE ยท (^) Hazardous Air Pollutants Substance is not listed. ยท Proposition 65 ยท Chemicals known to cause cancer: Substance is not listed. ยท Chemicals known to cause reproductive toxicity for females: (^) Substance is not listed. ยท Chemicals known to cause reproductive toxicity for males: Substance is not listed. ยท Chemicals known to cause developmental toxicity: (^) Substance is not listed.
ยท Carcinogenic categories ยท EPA (Environmental Protection Agency) Substance is not listed. ยท (^) TLV (Threshold Limit Value) Substance is not listed. ยท NIOSH-Ca (National Institute for Occupational Safety and Health) Substance is not listed. ยท (^) Chemical safety assessment: A Chemical Safety Assessment has not been carried out.
16 Other information All chemicals may pose unknown hazards and should be used with caution. This SDS applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this SDS. Cayman Chemical Company assumes no responsibility for incidental or consequential damages, including lost profits, arising from the use of these data. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this SDS is based on technical data judged to be reliable, Cayman Chemical Company assumes no responsibility for the completeness or accuracy of the information contained herein. ยท (^) Department issuing SDS: Environment protection department. ยท Contact: - ยท (^) Date of preparation / last revision 05/06/2021 / - (Contd. on page 8) US
Safety Data Sheet
acc. to OSHA HCS
Printing date 05/06/2021 Revision date 05/06/
Trade name: Benzocaine
(Contd. from page 7) ยท Abbreviations and acronyms: IMDG: International Maritime Code for Dangerous Goods DOT: US Department of Transportation IATA: International Air Transport Association EINECS: European Inventory of Existing Commercial Chemical Substances CAS: Chemical Abstracts Service (division of the American Chemical Society) NFPA: National Fire Protection Association (USA) HMIS: Hazardous Materials Identification System (USA) LC50: Lethal concentration, 50 percent LD50: Lethal dose, 50 percent PBT: Persistent, Bioaccumulative and Toxic vPvB: very Persistent and very Bioaccumulative NIOSH: National Institute for Occupational Safety OSHA: Occupational Safety & Health TLV: Threshold Limit Value PEL: Permissible Exposure Limit REL: Recommended Exposure Limit Skin Sens. 1: Skin sensitisation โ Category 1 STOT SE 1: Specific target organ toxicity (single exposure) โ Category 1 ยท (^) *** Data compared to the previous version altered.** US
