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NSG || 533 ||Opioid ||Quiz ||with ||correct ||
answers ||
Endogenous ||opioid ||peptides Small ||molecules ||that ||are ||naturally ||produced ||in ||the ||CNS || and ||in ||various ||glands ||throughout ||the ||body, ||such ||as ||the || pituitary ||and ||adrenal ||glands. ||Consists ||of ||endorphins, || enkephalins, ||dynorphins, ||and ||nociceptins. Mechanism ||of ||action ||for ||opioids Stimulating ||opioid ||u-receptors ||in ||the ||CNS. ||Pure ||agonists || (morphine) ||bind ||to ||u-receptors ||to ||produce ||analgesia ||that || increases ||with ||dose ||without ||a ||ceiling ||effect. ||Partial || agonists ||at ||the ||u-receptor ||(Buprenorphine, ||tramadol) || cause ||less ||conformational ||change ||and ||receptor || activation ||than ||full ||agonists. Indications ||for ||initiating ||opioid ||therapy Used ||when ||benefits ||outweigh ||risks ||associated ||with || opioids ||such ||as ||abuse. ||Used ||for ||acute ||pain ||(including || post-surgical) ||from ||under ||a ||month, ||and ||chronic ||pain.
Tolerance the ||diminishing ||effect ||with ||regular ||use ||of ||the ||same ||dose || of ||a ||drug, ||requiring ||the ||user ||to ||take ||larger ||and ||larger || doses ||before ||experiencing ||the ||drug's ||effect Dependence the ||condition ||that ||results ||when ||the ||brain ||develops ||a || chemical ||need ||for ||a ||drug ||and ||cannot ||function ||normally || without ||it Addiction A ||physiological ||or ||psychological ||dependence ||on ||a ||drug Neuralgia nerve ||pain Analgesia
How ||should ||a ||proper ||dose ||of ||opioid ||be ||determined Convert ||each ||dose ||of ||opioid ||to ||MME ||by ||multiplying ||the || daily ||dosage ||for ||each ||opioid ||by ||its ||conversion ||factor. Neuropathic ||pain ||management Gabapentin ||or ||pregabalin, ||transdermal ||lidocaine, ||TCA's, || SNRI's ||(Duloxetine), ||generally ||no ||opioids.. Adjunct ||and ||"other" ||medications ||to ||manage ||pain Acetaminophen, ||NSAIDs ||(if ||can ||be ||tolerated), || gabapentin, ||pregabalin, ||duloxetine, ||lidocaine, || anticonvulsants, ||corticosteroids Recommended ||guidelines ||for ||prescribing ||opioids Prescribe ||at ||the ||lowest ||effective ||dose, ||tapering ||off ||when || done, ||evaluate ||risks ||and ||benefits ||of ||therapy, ||maximize || use ||of ||nonopioid ||therapy, ||monitor ||opioids ||and ||count ||of || opioids, ||educate ||the ||patient, ||involve ||pt ||in ||care
Genetic ||polymorphisms ||when ||considering ||opioids Can ||influence ||the ||shape ||and ||number ||of ||drug ||receptors, || affecting ||the ||intensity ||of ||response. ||Can ||require ||higher || doses ||of ||opioids ||to ||work. Adverse ||effects ||of ||opioids Effects ||include ||central ||nervous ||system ||depression, || respiratory ||depression, ||hypotension, ||flushing, || palpitations, ||constipation, ||nausea ||and ||vomiting, ||urinary || retention, ||itching, ||rash, ||and ||biliary ||tract ||spasm. Options ||available ||for ||medication-assisted ||treatment || (MAT) Buprenorphine ||(suboxone), ||methadone, ||and ||naltrexone Prescribing ||restrictions ||for ||MAT Must ||apply ||for ||federal ||approval ||to ||prescribe ||suboxone || prescription. ||Must ||take ||a ||course ||8-24 ||hours. ||Apply ||for ||a || special ||ID ||number ||from ||the ||DEA, ||subject ||pt ||records ||to || DEA ||scrutinization.
Insert ||the ||nozzle ||into ||one ||nostril ||until ||your ||fingers ||on || either ||side ||side ||of ||the ||nozzle ||are ||against ||the ||bottom ||of || the ||nose
