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capitulo 2 bioestadística, Ejercicios de Bioestadística

Ejercicios bioestadística sobre medidas de mortalidad

Tipo: Ejercicios

2022/2023

Subido el 17/02/2023

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1. Between 1971 and 1975, as part of the National Health and Nutrition Examination Survey (NHANES),
7,381 persons ages 4077 years were enrolled in a follow-up study.1 At the time of enrollment, each
study participant was classified as having or not having diabetes. During 19821984, enrollees were
documented either to have died or were still alive. The results are summarized as follows:
Of the men enrolled in the NHANES follow-up study, 3,151 were nondiabetic and 189 were diabetic. 1.1.
Calculate the ratio of non-diabetic to diabetic men.
2. A city of 4,000,000 persons has 500 clinics. Calculate the ratio of clinics per person.
3. Delaware’s infant mortality rate in 2001 was 10.7 per 1,000 live births.2 New Hampshire’s infant
mortality rate in 2001 was 3.8 per 1,000 live births. Calculate the ratio of the infant mortality rate in
Delaware to that in New Hampshire.
4. Calculate the proportion of men in the NHANES follow-up study who were diabetics.
5. Calculate the proportion of deaths among men.
6. In the study of diabetics, 100 of the 189 diabetic men died during the 13-year follow-up period.
Calculate the risk of death for these men.
7. In an outbreak of gastroenteritis among attendees of a corporate picnic, 99 persons ate potato salad,
30 of whom developed gastroenteritis. Calculate the risk of illness among persons who ate potato
salad.
8. Consider an outbreak of shigellosis in which 18 persons in 18 different households all became ill. If
the population of the community was 1,000, then the overall attack rate was 18 / 1,000 x 100% =
1.8%. One incubation period later, 17 persons in the same households as these “primary” cases
developed shigellosis. If the 18 households included 86 persons, calculate the secondary attack rate.
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  1. Between 1971 and 1975, as part of the National Health and Nutrition Examination Survey (NHANES), 7,381 persons ages 40–77 years were enrolled in a follow-up study.1 At the time of enrollment, each study participant was classified as having or not having diabetes. During 1982–1984, enrollees were documented either to have died or were still alive. The results are summarized as follows: Of the men enrolled in the NHANES follow-up study, 3,151 were nondiabetic and 189 were diabetic. 1.1. Calculate the ratio of non-diabetic to diabetic men.
  2. A city of 4,000,000 persons has 500 clinics. Calculate the ratio of clinics per person.
  3. Delaware’s infant mortality rate in 2001 was 10.7 per 1,000 live births.2 New Hampshire’s infant mortality rate in 2001 was 3.8 per 1,000 live births. Calculate the ratio of the infant mortality rate in Delaware to that in New Hampshire.
  4. Calculate the proportion of men in the NHANES follow-up study who were diabetics.
  5. Calculate the proportion of deaths among men.
  6. In the study of diabetics, 100 of the 189 diabetic men died during the 13-year follow-up period. Calculate the risk of death for these men.
  7. In an outbreak of gastroenteritis among attendees of a corporate picnic, 99 persons ate potato salad, 30 of whom developed gastroenteritis. Calculate the risk of illness among persons who ate potato salad.
  8. Consider an outbreak of shigellosis in which 18 persons in 18 different households all became ill. If the population of the community was 1,000, then the overall attack rate was 18 / 1,000 x 100% = 1.8%. One incubation period later, 17 persons in the same households as these “primary” cases developed shigellosis. If the 18 households included 86 persons, calculate the secondary attack rate.
  1. Investigators enrolled 2,100 women in a study and followed them annually for four years to determine the incidence rate of heart disease. After one year, none had a new diagnosis of heart disease, but 100 had been lost to follow-up. After two years, one had a new diagnosis of heart disease, and another 99 had been lost to follow-up. After three years, another seven had new diagnoses of heart disease, and 793 had been lost to follow-up. After four years, another 8 had new diagnoses with heart disease, and 392 more had been lost to follow-up. The study results could also be described as follows: No heart disease was diagnosed at the first year. Heart disease was diagnosed in one woman at the second year, in seven women at the third year, and in eight women at the fourth year of follow-up. One hundred women were lost to follow- up by the first year, another 99 were lost to follow-up after two years, another 793 were lost to follow-up after three years, and another 392 women were lost to follow-up after 4 years, leaving 700 women who were followed for four years and remained disease free. Calculate the incidence rate of heart disease among this cohort. Assume that persons with new diagnoses of heart disease and those lost to follow-up were disease-free for half the year, and thus contribute ½ year to the denominator.
  2. The diabetes follow-up study included 218 diabetic women and 3,823 nondiabetic women. By the end of the study, 72 of the diabetic women and 511 of the nondiabetic women had died. The diabetic women were observed for a total of 1,862 person years; the nondiabetic women were observed for a total of 36,653 person years. Calculate the incidence rates of death for the diabetic and non- diabetic women.
  3. In 2003, 44,232 new cases of acquired immunodeficiency syndrome (AIDS) were reported in the United States.5 The estimated mid-year population of the U.S. in 2003 was approximately 290,809,777.6 Calculate the incidence rate of AIDS in 2003.
  4. In a survey of 1,150 women who gave birth in Maine in 2000, a total of 468 reported taking a multivitamin at least 4 times a week during the month before becoming pregnant.7 Calculate the prevalence of frequent multivitamin use in this group.
  5. Figure represents 10 new cases of illness over about 15 months in a population of 20 persons. Each horizontal line represents one person. The down arrow indicates the date of onset of illness. The solid line represents the duration of illness. The up arrow and the cross represent the date of recovery and date of death, respectively.

14.1. Unintentional-injury-specific mortality rate for the entire population 14.2. All-cause mortality rate for 25–34 year olds 14.3. All-cause mortality among males 14.4 Unintentional-injury specific mortality among 25 to 34 year old males

  1. Between 1940 and 1949, a total of 143,497 incident cases of diphtheria were reported. During the same decade, 11,228 deaths were attributed to diphtheria. Calculate the death-to-case ratio.
  2. In an epidemic of hepatitis A traced to green onions from a restaurant, 555 cases were identified. Three of the case-patients died as a result of their infections. Calculate the case-fatality rate.
  3. Public health officials were called to investigate a perceived increase in visits to ships’ infirmaries for acute respiratory illness (ARI) by passengers of cruise ships in Alaska in 1998.13 The officials compared passenger visits to ship infirmaries for ARI during May–August 1998 with the same period in 1997. They recorded 11.6 visits for ARI per 1,000 tourists per week in 1998, compared with 5. visits per 1,000 tourists per week in 1997. Calculate the rate ratio.
  4. For each of the fractions shown below, indicate whether it is a ratio, a proportion, a rate, or none of the three. A. Ratio B. Proportion C. Rate D. None of the above
  1. In 2001, a total of 15,555 homicide deaths occurred among males and 4,753 homicide deaths occurred among females. The estimated 2001 midyear populations for males and females were 139,813,000 and 144,984,000, respectively. 19.1. Calculate the homicide-related death rates for males and for females. 19.2. What type(s) of mortality rates did you calculate in Question 1? 19.3. Calculate the ratio of homicide-mortality rates for males compared to females.