Advanced Cryo-EM Services for High-Resolution Subcellular Organelle Structures, Slides of Biology

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Subcellular Organelle

structure service

Cryo-Electron Microscopy (Cryo-EM) can present samples in a native

state with imaging the sample’s intrinsic electron density, providing

direct visualization of biological macromolecules, such as protein,

nucleic acid, large complexes and so on. Conversely, X-ray

crystallography must require crystallization of the specimen within

non-physiological environments. The resolution of Cryo-EM maps has

been improved up to near-atomic resolution level. Thus Cryo-EM is

gaining popularity in structural biology.

At Creative Biostructure, we have the most advanced Electron

Microscopes equipments and software. In addition, Creative

Biostructure has a professional team for experimental design of

subcellular organelles separation and Cryo-ET data analysis.

The advantages of our service include:

The most advanced direct-electron detectors and image processing

software;

Allow near-atomic resolution structures to be calculated without

crystallization and only need a small amount of purified samples;

Provide the unique possibility to image organelle in their native

environment or in situ;

Visualize the interaction of proteins and cells, capture transient and

dynamic processes;

Bring a hope for further understanding of life mechanisms and

mysteries.

Creative Biostructure provides professional services of Cryo-EM. It is

possible to observe the structure of cells in the native state and provide

the detailed information of life.

Excerpt from:

https://www.creative-biostructure.com/Cryo-EM-for-

Subcellular-Organelles-598.htm