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WGU Pathophysiology D236 Study Guide Complete
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Describe how your body responds to an infection. T cells produce cytokines, which stimulate B cells. B cells produce antibodies. Identify role of DNA changes in congenital abnormalities. Mutations in genes or chromosomal abnormalities How does development disrupts congenital abnormalities? Alterations of DNA Describes factors that disrupt homeostasis and how disruptions affect wellbeing. (ex) Fluid and electrolyte shifts can cause n/v or dysrhythmias. Explain RAAS Renin-angiotensin-aldosterone system
Connective- RA, Scleroderma, Lupus Muscle - MS, Muscular dystrophy, Myasthenia Gravia Describe Lupus Inflammatory disorder characterized by joint pain and butterfly rash Describe Myasthenia Gravis It is an autoimmune disorder where antibodies attack own Ach receptors. This causes weakness of skeletal muscles over the course of the day, along with ptosis, double vision, and difficulty swallowing. dermatitis inflammation of the skin eczema noninfectious, inflammatory skin disease characterized by redness, blisters, scabs, and itching decubitus ulcer sore caused by lying down for long periods of time Fungal infections superficial, localized skin conditions or deep tissue infections caused by exposure to spores may or may not be transmitted benign neoplasm noncancerous growths, stationary, distinct borders malignant neoplasm uncontrolled new tissue growth, irregular borders, spreads Osteoporosis The loss of bone mass often due to age, causing the bones to become porous, brittle, and easily fractured. osteomalacia disease marked by softening of the bone caused by calcium and vitamin D deficiency myoglobin red pigment that stores oxygen in muscle cells Bursa fluid-filled sac that allows for easy movement of one part of a joint over another Rickets a vitamin D deficiency in children, resulting in soft bones Degenerative disk disease A condition in which an intervertebral disk loses its normal structural integrity as a result of wear and tear, acute or repeated injuries or aging Paget disease Chronic inflammation of bones, resulting in thickening and softening of bones, that can occur in any bone but most commonly affects the long bones of the legs, the lower spine, the pelvis, and the skull communiuted fracture splintered into many pieces Three types of skin cancer
cerebral contusion the bruising of brain tissue as the result of a head injury that causes the brain to bounce against the rigid bone of the skull; symptoms: ringing in ears, severe headache, n/v. TIA vs CVA TIA = -result when a cerebral artery is temp blocked and decreases blood flow to brain Stroke= artery completely blocked leading to death of brain and permanent loss of certain functions multiple sclerosis A chronic, irreversible disease of the central nervous system marked by damage to the myelin sheath. Plaques occur in the brain and spinal cord causing tremor, weakness, incoordination, paresthesia, and disturbances in vision and speech aneurysm ballooning of a weakened portion of an arterial wall thrombus vs embolus Thrombus = clot in arteries embolus = dislodged traveling clot in arteries, blocks blood flow Artherosclerosis Hardening and narrowing of the arteries due to buildup of cholesterol plaques 1.endothelial injury 2.foam cell formation 3.fatty streak formation angina pectoris chest pain, which may radiate to the left arm and jaw, that occurs when there is an insufficient supply of blood to the heart muscle myocardial infarction the occlusion of one or more coronary arteries caused by plaque buildup (heart attack) endocaritis inflammation of the inner lining of the heart peridcarditis inflammation of the pericardium (sack surrounding heart) benign vs malignant hypertension benign - "essential hypertension", chronic vascular damage due to sodium retention. malignant - acute vascular damage due to renin release communicable disease A disease that can be spread from one person or species to another. infectious disease A disease that is caused by a pathogen and that can be spread from one individual to another. myocardial infarction causes damage to arteries of : brain, retina, heart, kidneys. what is expected in right sided heart falure JVD what characterizes hypertensive crisis
systolic BP > 180 types of anemia
risk factors for bladder cancer Smoking**, occupational exposure to dyes (benzenes, aromatic amines), Hx of gross hematuria, >40 y/o, hx of urologic disorder, Hx of irritative voiding symptoms, Hx of UTI, analgesic abuse, history of pelvic irradiation See 50 more