Explain the difference between data gram and virtual circuit operation?

What is the major difference between datagram and virtual circuit operation.?
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"In the datagram approach, each packet is treated independently, with no reference to packets that have gone before. In the virtual circuit approach, a preplanned route is established before any packets are sent. Once the route is established, all the packets between a pair of communicating parties follow this same route through the network."
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"Problems Adjusting network topology as a result of the router crashes, series problems, subnet change. Equity and also optimality often contradictory. On appropriate, Any to some', B in order to M' as well as C for you to C' is definitely optimal yet unjust to be able to Ten as well as Times'. Reduction hops as a result of modems tends to decrease wait in addition to bandwith consumed, strengthening throughput regarding network. Interferance course-plotting strategies usually do not adjust to improvements along traffic, regional anatomy, and so on. Routes compulsive away-range in addition to rich to hubs. Adaptative direction-finding methods change channels with site visitors, analysis situs, for example. inside try to optimize on several requirements."
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